Evidence map›Paper›PMID 41700854›Full record

ArticleJournal of medical virology2026

TTV Load Mirrors Local Immunity and Tracks HPV Positivity in the Anogenital Tract.

Lilia Cinti, Innocenza Palaia, Alessandra Pierangeli, Gabriella D'ettorre, Eugenio Nelson Cavallari, Guido Antonelli, Piergiorgio Roberto

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medical virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lilia CintiLaboratory of Microbiology and Virology, Department of Molecular Medicine, Sapienza University of Rome, Rome, Latium, Italy.
Innocenza PalaiaUniversity Hospital "Policlinico Umberto I", Rome, Italy.
Alessandra PierangeliLaboratory of Microbiology and Virology, Department of Molecular Medicine, Sapienza University of Rome, Rome, Latium, Italy.ORCID https://orcid.org/0000-0003-0633-360X
Gabriella D'ettorreUniversity Hospital "Policlinico Umberto I", Rome, Italy.
Eugenio Nelson CavallariUniversity Hospital "Policlinico Umberto I", Rome, Italy.
Guido AntonelliLaboratory of Microbiology and Virology, Department of Molecular Medicine, Sapienza University of Rome, Rome, Latium, Italy.ORCID https://orcid.org/0000-0002-2533-2939
Piergiorgio RobertoLaboratory of Microbiology and Virology, Department of Molecular Medicine, Sapienza University of Rome, Rome, Latium, Italy.ORCID https://orcid.org/0000-0002-9170-3654

Funding

Guido Antonelli and by Sapienza funding Avvio alla Ricerca - Tipo 2 AR22419073556E13the Italian Ministry of University and Research 2022ZRNTHWUniversity of Rome La Sapienza (Ricerca scientifica, progetti piccoli)
6 · The paper itself

Abstract

Torquetenovirus load has been proposed as an immunomodulated biomarker of host immune status, yet its behavior in situ within HPV-infected mucosa remains poorly defined. We conducted a retrospective cross-sectional study of 220 patients undergoing HPV screening (181 cervical swabs, 39 anal brushings). HPV was genotyped with Allplex™ HPV28, and TTV load was quantified by in-house RT-qPCR and expressed as log

Indexed as

Anal CanalDNA Virus InfectionsHuman Papillomavirus VirusesPapillomaviridaePapillomavirus InfectionsTorque teno virusViral LoadAdultCoinfectionCross-Sectional StudiesDNA, ViralFemaleGenotypeHumansMaleMiddle AgedDNA, ViralCo‐infectiongenotype co‐occurrencehuman papillomavirus (HPV)mucosal immunityTorque teno virus (TTV)Viral load

Identifiers

PMID41700854
PMCPMC12911470

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.