ReviewBioscience reports2026
The role of growth hormone in metastasis and angiogenesis of breast cancer.
Review in Bioscience reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Breast cancer is a complex disease which has many factors affecting its progression and metastasis. Although steroid hormones, especially oestrogen, are most commonly associated with breast cancer, growth hormone (GH) also plays a substantial role in its development and spread via the activation of downstream signalling pathways and the regulation of growth factors such as insulin-like growth factor-1 (IGF-1) and the vascular endothelial growth factor (VEGF). Breast cancer patients usually have elevated levels of GH and IGF-1 in their circulation. Growth hormone receptor (GHR) signalling enhances migratory ability of tumour cells and excess IGF-1 production promotes angiogenesis. Gaining a full understanding of the mechanisms behind GH and breast cancer will allow researchers to develop more therapeutics to treat this devastating disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.