Evidence map›Paper›PMID 41700718›Full record

ArticleFEMS microbiology ecology2026

From bystander to key player: unveiling the gut microbiota's role in mediating cyanobacterial toxicity in aquatic animals.

Maiwenn Le Meur, Ellen Decaestecker, Xuexiu Chang, Benjamin Marie, Sébastien Duperron

Abstract read
In one paragraph

Article in FEMS microbiology ecology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maiwenn Le MeurUMR 7245 MCAM, Molécules de Communication et Adaptation des Microorganismes, Muséum national d'Histoire naturelle, 12 rue Buffon, 75005 Paris, France.
Ellen DecaesteckerMicrobiome EcoEvo Unit, Aquatic Biology, Interdisciplinary Research Facility Life Sciences, KU Leuven, E. Sabbelaan, 53 8500 Kortrijk, Belgium.ORCID 0000-0001-6328-5283
Xuexiu ChangYunnan Collaborative Innovation Center for Plateau Lake Ecology and Environmental Health, College of Agronomy and Life Sciences, Kunming University, Kunming 650214, China.
Benjamin MarieUMR 7245 MCAM, Molécules de Communication et Adaptation des Microorganismes, Muséum national d'Histoire naturelle, 12 rue Buffon, 75005 Paris, France.
Sébastien DuperronUMR 7245 MCAM, Molécules de Communication et Adaptation des Microorganismes, Muséum national d'Histoire naturelle, 12 rue Buffon, 75005 Paris, France.ORCID 0000-0002-6422-6821

Funding

Agence National de sécurité Sanitaire de l'alimentation, de l'Environnement et du travail ANSES 22-EST-111CNRSDIM ONE HEALTH 9552024PHDMNHN
6 · The paper itself

Abstract

Cyanobacterial blooms represent one prevalent stressor in aquatic ecosystems worldwide, exposing aquatic animals to complex mixtures of live cells and dissolved bioactive compounds, including cyanotoxins. The gut microbiota, which plays fundamental roles in digestion, immunity, and metabolic regulation, has been recognized as a key interface between environmental stressors and host health. Exposure to cyanobacteria occurs primarily through ingestion, making the gut the main site of interaction with live cells, cyanobacterial metabolites, and associated bacteria. While dissolved bioactive compounds can also penetrate via gills and skin, their role is secondary in most animals. Understanding how cyanobacteria interact with the host gut microbiota is therefore essential to fully assess their impacts on animal health. This review summarizes current knowledge of gut microbiota responses to cyanobacterial stress in crustaceans, mollusks, and chordates, highlighting dynamic and context-dependent changes in microbial communities. We discuss the cascading effects on host physiology, immune function, and metabolic homeostasis, and explore how the microbiota may modulate host resilience, including potential roles in cyanotoxin degradation.

Indexed as

aquatic animalscyanobacteriacyanotoxinsholobiont

Identifiers

PMID41700718
PMCPMC12940133

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.