Evidence map›Paper›PMID 41700620›Full record

ArticleMolecular pain

Beyond restless sleep: A cross-sectional study of obstructive sleep apnea risk, aging biomarkers, and chronic low back pain.

Khalid W Freij, Fiona Bat Agbor, Philemon Domoyeri, Kiari R Kinnie, Asia M Wiggins, Demario S Overstreet, Tammie L Quinn, Shivraj S Grewal, S Justin Thomas, Walid W Freij and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular pain. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Khalid W FreijDepartment of Acute, Chronic & Continuing Care, Nurse Anesthesia Program, School of Nursing, The University of Alabama at Birmingham, Birmingham, AL, USA.ORCID 0009-0001-1795-2927
Fiona Bat AgborDepartment of Acute, Chronic & Continuing Care, Nurse Anesthesia Program, School of Nursing, The University of Alabama at Birmingham, Birmingham, AL, USA.ORCID 0009-0006-9169-5064
Philemon DomoyeriDepartment of Acute, Chronic & Continuing Care, Nurse Anesthesia Program, School of Nursing, The University of Alabama at Birmingham, Birmingham, AL, USA.ORCID 0009-0000-1822-0712
Kiari R KinnieDepartment of Acute, Chronic & Continuing Care, Nurse Anesthesia Program, School of Nursing, The University of Alabama at Birmingham, Birmingham, AL, USA.
Asia M WigginsDepartment of Psychology, College of Arts and Sciences, The University of Alabama at Birmingham, Birmingham, AL, USA.
Demario S OverstreetDepartment of Surgery, Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, AL, USA.
Tammie L QuinnDepartment of Psychology, College of Arts and Sciences, The University of Alabama at Birmingham, Birmingham, AL, USA.
Shivraj S GrewalDepartment of Psychology, College of Arts and Sciences, The University of Alabama at Birmingham, Birmingham, AL, USA.
S Justin ThomasDepartment of Psychiatry & Behavioral Neurobiology, Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, AL, USA.
Walid W FreijVaughan Regional Medical Center Sleep Center, Vaughan Regional Medical Center, Selma, AL, USA.
Shameka L CodyCapstone College of Nursing, The University of Alabama, Tuscaloosa, AL, USA.
Michael A OwensDepartment of Psychiatry & Behavioral Neurobiology, Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, AL, USA.
Robert E SorgeDepartment of Psychology, College of Arts and Sciences, The University of Alabama at Birmingham, Birmingham, AL, USA.
Burel R GoodinDepartment of Anesthesiology, School of Medicine, Washington University, St. Louis, MO, USA.
Edwin N ArokeDepartment of Acute, Chronic & Continuing Care, Nurse Anesthesia Program, School of Nursing, The University of Alabama at Birmingham, Birmingham, AL, USA.ORCID 0000-0002-8355-0870

Funding

Racial and Socioeconomic Differences in Chronic Low Back PainR01MD010441 · NIMHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GOODIN, BUREL R., SORGE, ROBERT · 2017 to 2021
$2.6M
Epigenomic and Gene Expression Signatures of Racial Differences in Chronic Low Back PainR01AR079178 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI AROKE, EDWIN NGOMUEH · 2021 to 2024
$1.6M
NIAMS NIH HHS R01 AR079178NIMHD NIH HHS R01 MD010441
6 · The paper itself

Abstract

This secondary data analysis aimed to determine the nature of the relationship between obstructive sleep apnea (OSA) risk, biological age acceleration, and nonspecific chronic low back pain (CLBP). In total, 199 adults aged 18-82 years who filled both STOPBANG and pain questionnaires subsetted for secondary analysis. Based on the STOPBANG questionnaire, 104 had a low OSA risk and 95 had an intermediate or high OSA risk. Dunedin Pace of Aging Computed from the Epigenome (DunedinPACE), Horvath's, Hannum's, PhenoAge, and GrimAge clocks were used to determine biological age and pace of biological aging. Individuals with low OSA risk reported increased DunedinPACE compared to those with intermediate/high OSA risk (

Indexed as

AgingBiomarkersChronic PainLow Back PainSleepSleep Apnea, ObstructiveAdolescentAdultAgedAged, 80 and overCross-Sectional StudiesFemaleHumansMaleMiddle AgedRisk FactorsBiomarkersDunedinPACEnonspecific chronic low back painobstructive sleep apneapace of biological agingpain disparities

Identifiers

PMID41700620
PMCPMC12967356

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.