Evidence map›Paper›PMID 41700226›Full record

ArticleCureus2026

Herb-Induced Liver Injury (HILI) Associated With Asowosi (Momordica charantia): A Case Report.

Daniela Guerra, Elham Shams, Pedro Igorra, Sarah Nickle, Muhammad Aziz

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Daniela GuerraMedicine, Herbert Wertheim College of Medicine, Florida International University, Miami, USA.
Elham ShamsInternal Medicine, Jackson Memorial Hospital, Miami, USA.
Pedro IgorraMedicine, Herbert Wertheim College of Medicine, Florida International University, Miami, USA.
Sarah NickleTranslational Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, USA.
Muhammad AzizInternal Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herbal remedies are widely used for various health purposes, yet their potential to cause adverse effects is often overlooked. Asowosi, also known as bitter melon, is one such plant incorporated into traditional medicine practices for blood sugar management. This case study presents the comprehensive findings regarding a 38-year-old male who initially presented with transaminitis and weakness. The cause of the patient's elevated liver enzymes was unclear, as he reported occasional alcohol consumption. However, upon further questioning, he disclosed two to three weeks of herbal remedy use, including Asowosi. The supplement had been selected for its accessibility and familiarity. While the exact mechanism of injury in this case remains unclear, herbal products can have physiologic effects that warrant consideration during diagnostic evaluation. Determining the etiology of this patient's acute liver injury was challenging due to the limited clinical information available on Asowosi. After supportive care and discontinuation of the herbal remedies, the patient's condition improved, and liver histology supported a diagnosis of herb-induced liver injury (HILI). This case underscores the importance of including herbal and nonprescription products in the differential diagnosis of unexplained liver injury and encourages prompt recognition and reporting of similar cases.

Indexed as

asowosibitter melondietary supplementsherbal hepatotoxicitynaturopathytransaminitis

Identifiers

PMID41700226
PMCPMC12906716

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.