Evidence map›Paper›PMID 41700167›Full record

ReviewWorld journal of gastrointestinal endoscopy2026

Relationship between the appendix and ulcerative colitis: A new discovery.

Xu-Jia Wu, Reng-Yun Xiang, Pan Gong, Qian Chen, Xue-Feng Li

Abstract readReview
In one paragraph

Review in World journal of gastrointestinal endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Appendix in ulcerative colitis pathogenesis and therapy: An updated narrative review.World journal of gastrointestinal pathophysiology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xu-Jia WuDepartment of Gastroenterology, The First Affiliated Hospital of Jishou University, Jishou 416000, Hunan Province, China.
Reng-Yun XiangDepartment of Gastroenterology, The First Affiliated Hospital of Jishou University, Jishou 416000, Hunan Province, China.
Pan GongDepartment of Gastroenterology, The First Affiliated Hospital of Jishou University, Jishou 416000, Hunan Province, China.
Qian ChenDepartment of Pathology, The First Affiliated Hospital of Jishou University, Jishou 416000, Hunan Province, China.
Xue-Feng LiDepartment of Gastroenterology, The First Affiliated Hospital of Jishou University, Jishou 416000, Hunan Province, China. longs9877@aliyun.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The appendix was once considered to be vestigial and useless organ. However, in recent years, research has confirmed that the appendix is associated with human immune function and exerts an anti-inflammatory effect through regulating the gut microbiota. Ulcerative colitis (UC) is a chronic and nonspecific inflammatory bowel disease associated with genetics, the environment, immunity, and alterations in the gut microbiota. Multiple studies have shown that the appendix and UC are closely related. With the advent of ultraslim subscopes allowing direct visualization (cholangioscopes), innovative methods for endoscopic diagnosis and treatment of appendicitis with appendix preservation have been successfully implemented. This has not only shifted the traditional approach to diagnosing and treating appendicitis, but has also opened the way for new insights and discoveries in exploring the relationship between the appendix and UC.

Indexed as

AppendixGut microbiotaImmunityInflammationUlcerative colitis

Identifiers

PMID41700167
PMCPMC12906223

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.