Evidence map›Paper›PMID 41700156›Full record

ArticleWorld journal of gastrointestinal endoscopy2026

Endoscopic ultrasound-guided liver biopsy: Are we ready for routine use?

Filippo Antonini, Andrea Anderloni, Carlo Fabbri, Ilaria Tarantino, Antonio Facciorusso

Abstract readEditorial
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of gastrointestinal endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Filippo AntoniniGastroenterology and Interventional Endoscopy Unit, C. e G. Mazzoni Hospital, Ascoli Piceno 63100, Italy. filippore@yahoo.it.
Andrea AnderloniDepartment of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia 27100, Italy.
Carlo FabbriGastroenterology and Digestive Endoscopy Unit, Forlì-Cesena Hospitals, Ausl Romagna, Forlì 47121, Italy.
Ilaria TarantinoGastroenterology and Hepatology Unit, IRCCS ISMETT, UPMC Italy, Palermo 90127, Italy.
Antonio FacciorussoGastroenterology Unit, Department of Experimental Medicine, University of Salento, Lecce 73100, Puglia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endoscopic ultrasound-guided liver biopsy (EUS-LB) is increasingly used for the evaluation of parenchymal liver disease, with recent multicenter data demonstrating high diagnostic yield and a low rate of serious adverse events. While EUS-LB offers technical flexibility through different needle sizes, suction techniques, and limited passes, its overall diagnostic outcomes, including specimen length, portal tract count, and sample adequacy, are comparable to standard percutaneous liver biopsy. Despite these encouraging results, EUS-LB is more invasive, requiring sedation and endoscopic expertise, and is substantially more costly than percutaneous-liver biopsy. Therefore, while EUS-LB is valuable in select clinical scenarios, current evidence does not support its routine use for parenchymal liver disease, and further prospective studies are needed to define its role relative to established percutaneous approaches.

Indexed as

Diagnostic yieldEndoscopic ultrasound-guided-fine-needle biopsyEndoscopic ultrasound-guided liver biopsyParenchymal liver diseasePercutaneous liver biopsy

Identifiers

PMID41700156
PMCPMC12898182

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.