Evidence map›Paper›PMID 41700141›Full record

ArticleEJHaem2026

Fluoroquinolone Prophylaxis Reduces Intensive Care Unit Admission and

Charles J Weeks, Sujith Abbagoni, Faizan Boghani, Priyanka Menon, Matthew Gold, Chandini Kannan, Ozal Ismayilov, Mark Dalgetty, Anvay Shah, Lydia Delay and 7 more

Abstract read
In one paragraph

Article in EJHaem, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Charles J WeeksMedical College of Georgia Augusta Georgia USA.
Sujith AbbagoniMedical College of Georgia Augusta Georgia USA.
Faizan BoghaniMedical College of Georgia Augusta Georgia USA.
Priyanka MenonMedical College of Georgia Augusta Georgia USA.
Matthew GoldDepartment of Internal Medicine Wellstar-MCG Hospital Augusta Georgia USA.
Chandini KannanDepartment of Internal Medicine Wellstar-MCG Hospital Augusta Georgia USA.
Ozal IsmayilovGeorgia Cancer Center Augusta Georgia USA.
Mark DalgettyGeorgia Cancer Center Augusta Georgia USA.
Anvay ShahGeorgia Cancer Center Augusta Georgia USA.
Lydia DelayMedical College of Georgia Augusta Georgia USA.
Heeju LimMedical College of Georgia Augusta Georgia USA.
Mohammad MianGeorgia Cancer Center Augusta Georgia USA.
Andrea ClarkeGeorgia Cancer Center Augusta Georgia USA.
Locke BryanGeorgia Cancer Center Augusta Georgia USA.
Jorge CortesGeorgia Cancer Center Augusta Georgia USA.
Anand JillellaGeorgia Cancer Center Augusta Georgia USA.
Vamsi KotaGeorgia Cancer Center Augusta Georgia USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Patients with acute myeloid leukemia (AML) undergoing induction chemotherapy are at high-risk of bloodstream infections, including central line-associated bloodstream infections (CLABSI) or mucosal barrier injury-related infections (MBI-LCBI). The impact of fluoroquinolone (FQ) prophylaxis on MBI-LCBI, Methods: We retrospectively reviewed adults with AML receiving induction chemotherapy between 2010 and 2022. Patients were grouped by receipt of FQ prophylaxis. Primary outcomes were incidence of CLABSI, and MBI-LCBI. Secondary outcomes included neutropenic fever, ICU admission, length of stay, and Results: Among 195 patients, 88 (45.1%) received FQ prophylaxis. CLABSI rates were 8.0% with prophylaxis versus 15.0% without ( Conclusions: In this cohort, FQ prophylaxis did not significantly reduce bloodstream infections but was associated with fewer ICU admissions and lower rates of

Indexed as

acute myeloid leukemiabloodstream InfectionsClostridioides difficilefluoroquinolonesinduction chemotherapyintensive care unit

Identifiers

PMID41700141
PMCPMC12906835

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.