Evidence map›Paper›PMID 41700116›Full record

ArticleJournal of the American Chemical Society2026

Potassium Bisulfite's Role in Developing a Robust Platform for Enantioenriched

Jake D Selingo, Jacob R King, Barbara Pio, Andrew J Neel, Yu-Hong Lam, Robert S Paton, Matthew L Maddess, Andrew McNally

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jake D SelingoDepartment of Chemistry, Colorado State University, Fort Collins, Colorado 80523, United States.
Jacob R KingDepartment of Chemistry, Colorado State University, Fort Collins, Colorado 80523, United States.
Barbara PioDepartment of Discovery Chemistry, Merck & Co. Inc., Rahway, New Jersey 07065, United States.
Andrew J NeelDepartment of Process Research and Development, Merck & Co. Inc., Boston, Massachusetts 02115, United States.ORCID 0000-0003-2872-5292
Yu-Hong LamComputational and Structural Chemistry, Merck & Co. Inc., Rahway, New Jersey 07065, United States.ORCID 0000-0002-4946-1487
Robert S PatonDepartment of Chemistry, Colorado State University, Fort Collins, Colorado 80523, United States.ORCID 0000-0002-0104-4166
Matthew L MaddessDepartment of Discovery Chemistry, Merck & Co. Inc., Boston, Massachusetts 02115, United States.ORCID 0000-0002-7273-528X
Andrew McNallyDepartment of Chemistry, Colorado State University, Fort Collins, Colorado 80523, United States.ORCID 0000-0002-8651-1631

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Piperidines are prominent scaffolds in medicinal chemistry. However, methods that incorporate chiral

Identifiers

PMID41700116
PMCPMC12964407

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.