Evidence map›Paper›PMID 41699920›Full record

ArticleBrain and behavior2026

Findings on Impact of Circadian Genes and Bipolar Disorder: A Bibliometric Analysis From 1996 to 2024.

Zhuoer Ruan, Jie Zhu

Abstract read
In one paragraph

Article in Brain and behavior, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Zhuoer RuanDepartment of Psychiatry, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Jie ZhuDepartment of Psychiatry, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe disturbances of circadian genes are implicated in the pathophysiology of bipolar disorder (BD). This bibliometric analysis aims to explore global trends and hotspots in research on circadian genes and BD.

designA bibliometric analysis.

methodsA systematic search was carried out on the Web of Science Core Collection (WoSCC) database to collect publications regarding circadian genes and BD. Subsequently, bibliometric analysis and visualization utilized VOSviewer (V 1.6.20), CiteSpace (V 6.3.R1), and the R package "Bibliometrix" (V 4.3.3).

resultsThe 400 articles involved 2405 authors from 1649 institutions, citing 18,840 sources in 166 journals. The number of publications has been consistently rising, with a 9.88% annual growth rate. The USA, Italy, and China dominated with the most articles. The most cited articles focused on the genetics of circadian disorders. The top institutions were the University of California system, the University of California, San Diego, and Université Paris. High-impact authors included McClung Colleen A., McCarthy Michael J., and Benedetti Francesco. The top journals by H-index were Chronobiology International, Journal of Affective Disorders, and American Journal of Medical Genetics. The keyword co-occurrence analysis revealed focus on "depression," "neurons," "light therapy," "genome wide association," and "lithium." The burst keywords highlighted the latest trends, including "sleep" and "brain," with consistent emphasis on "risk."

conclusionThis bibliometric analysis provides insights into the global trends and hotspots of research on circadian genes and BD. The hotspots are on symptoms, genetic associations, and treatment in BD, with frontiers exploring sleep patterns, brain functions, and risk factors.

Indexed as

BibliometricsBipolar DisorderCircadian RhythmHumansbibliometricsbipolar disordercircadian genes

Identifiers

PMID41699920
PMCPMC12910130

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.