Evidence map›Paper›PMID 41699888›Full record

ArticleNMR in biomedicine2026

Noninvasive 11.7-T Magnetic Resonance Spectroscopy and Imaging Reveals Retinal Metabolic Alterations Induced by Blue Light Exposure.

Lacramioara Samoila, Alexandru Farcasanu, Simion Simon, Ede Bodoki, Ovidiu Samoila, Oliviu Vostinaru, Elena Dinte, Andreea Elena Bodoki, Dan Iudean, Calin Muresan and 1 more

Abstract read
In one paragraph

Article in NMR in biomedicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lacramioara SamoilaDepartment of Physiology, "Iuliu Hațieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Alexandru FarcasanuInstitute for Interdisciplinary Research in Bio-Nano-Science, Preclinical MRI Center (INSPIRE Platform), Babeș-Bolyai University, Cluj-Napoca, Romania.
Simion SimonInstitute for Interdisciplinary Research in Bio-Nano-Science, Preclinical MRI Center (INSPIRE Platform), Babeș-Bolyai University, Cluj-Napoca, Romania.
Ede BodokiDepartment of Analytical Chemistry, "Iuliu Hațieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Ovidiu SamoilaDepartment of Ophthalmology, "Iuliu Hațieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Oliviu VostinaruDepartment of Pharmacology, Physiology and Physiopathology, "Iuliu Hațieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.ORCID https://orcid.org/0000-0003-4505-4005
Elena DinteDepartment of Pharmaceutical Technology and Biopharmaceutics, "Iuliu Hațieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Andreea Elena BodokiGeneral and Inorganic Chemistry Department, "Iuliu Hațieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Dan IudeanFaculty of Electrical Engineering, Department of Electrotechnics and Measurements, Technical University, Cluj-Napoca, Romania.
Calin MuresanFaculty of Electrical Engineering, Department of Electrotechnics and Measurements, Technical University, Cluj-Napoca, Romania.
Simona ClichiciDepartment of Physiology, "Iuliu Hațieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.

Funding

Ministry of Research, Innovation and Digitalization (MCID) 390005/23.10.2024Romanian Ministry of European Investment and Projects (MIPE) 352/390028/23.09.2021Romanian Ministry of European Investment and Projects (MIPE) G-2024-71962/23.10.2024
6 · The paper itself

Abstract

The eye is a complex structure, with multiple systems involved in focusing and detecting light. Among them, the retina, an integral component of the central nervous system, is considered the most vital and exhibits the highest metabolic activity among all tissues in the human body. It interacts with light, and excessive exposure, especially to blue light, is prone to produce degeneration, mainly through oxidative reactions. This mechanism is involved in age-related macular degeneration or diabetic retinopathy. Animal research is important, considering the high prevalence of these diseases; yet noninvasive procedures involving this research are lacking so far. Our objective was to apply an animal model of oxidative stress and monitor the metabolic changes using 11.7-T

Indexed as

Blue LightProton Magnetic Resonance SpectroscopyRetinaAnimalsMagnetic Resonance SpectroscopyMaleOxidative StressRatsage‐related macular degenerationblue lightmagnetic resonance spectroscopyretina

Identifiers

PMID41699888
PMCPMC12910191

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.