Evidence map›Paper›PMID 41699874›Full record

ArticlePhysiological reports2026

A secondary analysis of autonomic function during high-intensity interval exercise in adults with chronic stroke.

Bria L Bartsch, Saniya Waghmare, Mark Chertoff, Alicen A Whitaker-Hilbig, Sandra A Billinger

Abstract read
In one paragraph

Article in Physiological reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bria L BartschDepartment of Physical Therapy, Rehabilitation Science, and Athletic Training, University of Kansas Medical Center, Kansas City, Kansas, USA.
Saniya WaghmareDepartment of Neurology, University of Kansas Medical Center, Kansas City, Kansas, USA.
Mark ChertoffDepartment of Hearing and Speech, University of Kansas Medical Center, Kansas City, Kansas, USA.
Alicen A Whitaker-HilbigDepartment of Anesthesiology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Sandra A BillingerDepartment of Neurology, University of Kansas Medical Center, Kansas City, Kansas, USA.ORCID 0000-0002-1618-7207

Funding

University of Kansas Alzheimer's Disease Research Center (KU ADRC)P30AG072973 · NIA · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Mohammad Haeri · 2021 to 2026
$25.3M
Kansas University Training Program in Neurological and Rehabilitation SciencesT32HD057850 · NICHD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Jacob J. Sosnoff · 2009 to 2026
$3.4M
HHS | NIH | National Institute of Child Health and Human Development (NICHD) T32HD057850NIA NIH HHS P30 AG072973
6 · The paper itself

Abstract

Autonomic dysfunction post-stroke negatively affects the cardiovascular system's ability to regulate heart rate and blood pressure response to exercise. While high-intensity interval exercise (HIIE) is prescribed for stroke recovery, limited knowledge exists regarding how HIIE impacts autonomic function post-stroke. Characterize autonomic nervous system response to HIIE post-stroke. Heart rate and blood pressure were recorded during a 10-min recumbent stepper HIIE bout, cool-down, immediately post-exercise, and 30-min post-exercise. Fast Fourier Transformation was used to determine low and high frequency beat-to-beat blood pressure and heart rate power spectral density at all timepoints and baseline baroreflex sensitivity. We tested for differences in spectral data between timepoints using Friedman's test. The influence of arterial stiffness, age, and beta-blocker use on autonomic function was explored using linear regression. Twenty-seven participants completed HIIE. The autonomic nervous system response to HIIE was blunted with neither low nor high frequency blood pressure or heart rate variability exhibiting significant changes from baseline during exercise (p > 0.05). Baroreflex sensitivity was impaired, with age (p = 0.03), arterial stiffness (p < 0.01), and beta-blocker use (p = 0.03) affecting sensitivity. Autonomic function is blunted during HIIE post-stroke and likely attributed to impaired baroreflex sensitivity and arterial stiffness.

Indexed as

Autonomic Nervous SystemHigh-Intensity Interval TrainingStrokeStroke RehabilitationAgedBaroreflexBlood PressureFemaleHeart RateHumansMaleMiddle AgedVascular Stiffnessautonomic nervous systembaroreflex sensitivitycerebrovascular accidentheart rate variabilityspectral analysis

Identifiers

PMID41699874
PMCPMC12910124

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.