Evidence map›Paper›PMID 41699686›Full record

ArticleTrials2026

Group-based versus individual-based circuit training in elderly women with knee osteoarthritis: study protocol for a non-inferiority randomized controlled trial.

Clécio Lima-Lopes, Amanda Virginia Souza Lima Lopes, Rebeca Cajueiro Azevedo, Francis Trombini-Souza, Tarcísio Fulgêncio Alves da Silva

Abstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Clécio Lima-LopesMaster's and Doctoral Programs in Rehabilitation and Functional Performance, University of Pernambuco (UPE), Petrolina, Brazil. cleciolimopes@yahoo.com.br.ORCID http://orcid.org/0000-0003-4974-0985
Amanda Virginia Souza Lima LopesMaster's and Doctoral Programs in Rehabilitation and Functional Performance, University of Pernambuco (UPE), Petrolina, Brazil.
Rebeca Cajueiro AzevedoMaster's and Doctoral Programs in Rehabilitation and Functional Performance, University of Pernambuco (UPE), Petrolina, Brazil.
Francis Trombini-SouzaMaster's and Doctoral Programs in Rehabilitation and Functional Performance, University of Pernambuco (UPE), Petrolina, Brazil.
Tarcísio Fulgêncio Alves da SilvaMaster's and Doctoral Programs in Rehabilitation and Functional Performance, University of Pernambuco (UPE), Petrolina, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKnee osteoarthritis (KOA) is one of the most prevalent health issues, affecting approximately 67% of women over 60 years old. Clinical guidelines recommend individualized muscle training to treat this condition. However, a lack of human and financial resources hinders the delivery of this treatment. In response to this limitation, group training may be an alternative. Although a few studies have compared group and individual exercise for knee OA, none have tested the non-inferiority of group-delivered circuit training specifically in elderly women. Therefore, this study aims to compare the non-inferiority of a group-delivered muscle training program to the same individually delivered training in clinical and functional aspects in elderly women with KOA.

methodsThis is a randomized controlled non-inferiority trial with two arms, parallel groups, blinded evaluator, conducted in Petrolina-PE, evaluating women aged 60 or older. Participants randomly assigned will undergo an 8-week training, either in individual sessions (control group-IB) or as part of a group (intervention group-GB) of four participants, supervised by a physical therapist. Blind assessments at baseline, immediately post-intervention, and 4 weeks post-intervention will include feasibility, safety, and satisfaction analysis of the training program; pain; quality of life; and physical function. Data will be analyzed using the Statistical Package for Social Sciences (SPSS) version 22. Estimated marginal means of each clinical and functional outcome for both groups (IB and GB) will be compared using mixed-effects generalized linear models. The primary analysis will test our main hypothesis that group training is non-inferior to individualized training regarding the primary outcome: relative reduction (%) in the WOMAC questionnaire pain subscale. Confidence intervals of 95% will be calculated. A significance level of p < 0.05 will be adopted in all analyses. DISCUSSION: Expected results suggest that a group-based approach is not inferior to an individual one in this population.

trial registrationBrazilian Registry of Clinical Trials (ReBEC) ID: RBR-5bq9jh3. Registered on 18 August 2023. Link: http://www.ensaiosclinicos.gov.br ; Universal Trial Number (UTN) of World Health Organization: U1111-1289-2580.

Indexed as

Circuit-Based ExerciseExercise TherapyKnee JointOsteoarthritis, KneeAgedAge FactorsEquivalence Trials as TopicFemaleHumansMiddle AgedPain MeasurementQuality of LifeRandomized Controlled Trials as TopicRecovery of FunctionTime FactorsTreatment OutcomeElderlyExercise therapyKnee osteoarthritis

Identifiers

PMID41699686
PMCPMC12918481

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.