Evidence map›Paper›PMID 41699559›Full record

SynthesisBMC public health2026

Environmental health recommendations for Multidrug-Resistant Tuberculosis in low- and middle-income countries: a systematic review.

Amy Nel, Mary E Miller, Hanna-Andrea Rother

Abstract readSystematic Review
In one paragraph

Synthesis in BMC public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Key risk factors for pulmonary vs. extrapulmonary tuberculosis: a comparative study in Southwest Ethiopia.Journal of clinical tuberculosis and other mycobacterial diseases · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Amy NelDivision of Environmental Health, Department of Public Health, University of Cape Town, Observatory, Cape Town, 7925, South Africa.
Mary E MillerDivision of Environmental Health, Department of Public Health, University of Cape Town, Observatory, Cape Town, 7925, South Africa.
Hanna-Andrea RotherDivision of Environmental Health, Department of Public Health, University of Cape Town, Observatory, Cape Town, 7925, South Africa. andrea.rother@uct.ac.za.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe impact of environmental health risk factors on the optimization of health in MDR-TB infected individuals, as well as on the prevention of transmission to household contacts, is not well documented. Establishing the recommendations of environmental health risk factors for individuals living at home with MDR-TB will have important policy implications in LMICs, such as South Africa.

aimsThe study objectives were to identify current environmental health recommendations to optimize the health of individuals infected with MDR-TB, while living at home during the completion of their treatment regimen; and to prevent transmission to household contacts by individuals infected with MDR-TB.

methodsA systematic search of electronic databases was conducted in May 2021 using a predefined search strategy. An updated search was conducted in November 2023. All primary observational studies evaluating populations ≥ 13 years of age in LMICs were included if they examined the relationship between MDR-TB and the pre-defined exposures and outcomes.

resultsThe results of the systematic review highlighted an important potential relationship between environmental risk factors and optimising the health of individuals infected with MDR-TB. It also emphasized the role that promoting good environmental health practices may play in preventing the transmission to household contacts and should be incorporated into local health system strategies and global policy.

trial registrationThe protocol of this review was submitted and published on the PROSPERO register (Protocol registration number: CRD42021255946).

Indexed as

Developing CountriesEnvironmental HealthTuberculosis, Multidrug-ResistantHumansRisk FactorsSouth AfricaEnvironmental healthMulti drug-resistantOutcomesSystematic reviewTransmissionTuberculosis

Identifiers

PMID41699559
PMCPMC13014885

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.