Evidence map›Paper›PMID 41699487›Full record

Observational studyBMC cardiovascular disorders2026

Predictive value of platelet-to-lymphocyte ratio for new-onset atrial fibrillation after percutaneous coronary intervention in patients with ST-segment elevation myocardial infarction.

Yixuan Wu, Jiahua Liu, Lei Chen, Xinjia Du, Maochen Li, Yanfei Ren, Yuan Lu

Abstract readObservational Study
In one paragraph

Observational study in BMC cardiovascular disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yixuan WuDepartment of Cardiology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Jiahua LiuDepartment of Cardiology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Lei ChenDepartment of Cardiology, Tongji University School of Medicine, Shanghai Tenth People's Hospital, Shanghai, China.
Xinjia DuDepartment of Cardiology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Maochen LiDepartment of Cardiology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Yanfei RenDepartment of Cardiology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Yuan LuDepartment of Cardiology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China. drluyuan329@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveInflammation represents a key pathophysiological link between acute myocardial infarction and atrial fibrillation. Despite this, the platelet-to-lymphocyte ratio (PLR), as a composite inflammatory biomarker, remains underexplored for predicting new-onset atrial fibrillation (NOAF) specifically in patients with ST-segment elevation myocardial infarction (STEMI). This study aimed to evaluate the predictive value of PLR for in-hospital NOAF following percutaneous coronary intervention (PCI) in this population.

methodsThis was a single-center, retrospective observational study. A total of 335 patients diagnosed with STEMI at the Affiliated Hospital of Xuzhou Medical University from January 2023 to December 2023 were included. All patients underwent primary PCI within 12 h of symptom onset and received continuous electrocardiographic monitoring during hospitalization. Logistic regression analysis and receiver operating characteristic (ROC) curves were used to assess the relationship between PLR and the incidence of NOAF during hospitalization in STEMI patients.

resultsAmong the cohort, 30 patients (9.0%) developed NOAF during their hospital stay. Multivariable logistic regression, adjusted for potential confounders, identified age, systolic blood pressure, heart rate, and the coronary angiography-derived index of microcirculatory resistance (caIMR) as independent factors associated with NOAF. The PLR demonstrated good predictive performance for NOAF development, corresponding to an area under the curve (AUC) of 0.749 (95% CI: 0.664–0.834, P < 0.001). Incorporating PLR into a baseline clinical model significantly improved risk prediction, with a NRI of 0.608 (P = 0.001) and an IDI of 0.071 (P = 0.004).

conclusionThis study demonstrates that a high PLR is independently associated with in-hospital NOAF following primary PCI for STEMI. Furthermore, PLR offers significant improvement to the predictive capability of clinical risk models for NOAF, suggesting its utility in enhancing patient risk assessment.

Indexed as

Atrial FibrillationBlood PlateletsLymphocytesPercutaneous Coronary InterventionST Elevation Myocardial InfarctionAgedFemaleHumansIncidenceLymphocyte CountMaleMiddle AgedPlatelet CountPredictive Value of TestsRetrospective StudiesRisk AssessmentNOAFPCIPLRSTEMI

Identifiers

PMID41699487
PMCPMC13011377

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.