ArticleBMC anesthesiology2026
General anesthesia in patient with Hutchinson-Gilford Progeria syndrome: two case reports of dental treatment in the one patient.
Article in BMC anesthesiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundHutchinson-Gilford progeria syndrome (HGPS) is a rare genetic disorder that manifests itself in premature aging. Craniofacial and skeletal abnormalities, cardiovascular pathology, concomitant cerebrovascular diseases, and potential airway problems in HGPS significantly increase the degree of anesthetic risk and make anesthetic management more challenging in these patients. CASE PRESENTATION: We present the case of the girl with HGPS who undertook two episodes of dental treatment using general anesthesia at the ages of 8 and 10 years old. In both cases, airway was secured by fiberoptic intubation.
conclusionThis case increases the awareness of HGPS and the features of anesthesia in patients with HGPS. For long-term dental treatment, general anesthesia with tracheal intubation using fiberoptic access is the optimal method of anesthesia in these patients.
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