Evidence map›Paper›PMID 41699459›Full record

ArticleBMC genomics2026

Analysis of the TGA gene family and the role of SlTGA03 in tomato resistance to Meloidogyne enterolobii.

Junhong Chen, Cailan Wang, Mingming Shi, Huixia Li, Yonggang Liu, Ning Luo, Wei Guo

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Article in BMC genomics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Junhong ChenCollege of Plant Protection, Gansu Agricultural University, Lanzhou, 730070, China.
Cailan WangCollege of Plant Protection, Gansu Agricultural University, Lanzhou, 730070, China.
Mingming ShiCollege of Plant Protection, Gansu Agricultural University, Lanzhou, 730070, China.
Huixia LiCollege of Plant Protection, Gansu Agricultural University, Lanzhou, 730070, China. lihx@gsau.edu.cn.
Yonggang LiuInstitute of Plant Protection, Gansu Academy of Agricultural Sciences, Lanzhou, 730070, P.R. China.
Ning LuoCollege of Plant Protection, Gansu Agricultural University, Lanzhou, 730070, China.
Wei GuoCollege of Plant Protection, Gansu Agricultural University, Lanzhou, 730070, China.

Funding

National Key Research and Development Program of China 2023YFD1400400National Natural Science Foundation of China 32260654
6 · The paper itself

Abstract

backgroundTomato (Solanum lycopersicum) is an economically significant crop that faces numerous biotic stresses, particularly from Meloidogyne enterolobii.

resultsIn this study, we investigated the role of the TGA transcription factor (TF) family in tomato resistance to M. enterolobii. A total of ten putative SlTGAs were identified, and their characteristics, phylogenetic relationships, gene structures, and conserved motifs were analyzed. Phylogenetic analysis indicated that the tomato TGA family can be classified into five groups. Cis-regulatory element analysis revealed that the promoters of SlTGAs are enriched with hormone-responsive and stress-related elements. Furthermore, SlTGA03 was identified as playing a significant role in defense against M. enterolobii. Virus-induced gene silencing (VIGS) of SlTGA03 resulted in increased susceptibility to nematode infection, as evidenced by a higher number of galls and egg masses in silenced plants.

conclusionThese findings suggest that the SlTGA03 is essential for tomato to defend against root-knot nematodes and provide insights into the molecular mechanisms underlying nematode resistance in tomato.

Indexed as

Disease ResistanceMultigene FamilyPlant DiseasesPlant ProteinsSolanum lycopersicumTranscription FactorsTylenchoideaAnimalsGene Expression Regulation, PlantGene SilencingPhylogenyPromoter Regions, GeneticPlant ProteinsTranscription FactorsMeloidogyne enterolobiiSolanum lycopersicumTGA transcription factors

Identifiers

PMID41699459
PMCPMC13011514

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