Evidence map›Paper›PMID 41699277›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2026

Long term prognostic value of coronary atherosclerotic burden, myocardial perfusion and coronary flow capacity by

Emilia Zampella, Roberta Assante, Teresa Mannarino, Valeria Gaudieri, Adriana D'Antonio, Mariarosaria Panico, Valeria Cantoni, Roberta Green, Pietro Buongiorno, Mario Petretta and 3 more

Abstract read
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Article in European journal of nuclear medicine and molecular imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Emilia ZampellaDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, Naples, 80131, Italy.
Roberta AssanteDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, Naples, 80131, Italy.
Teresa MannarinoDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, Naples, 80131, Italy.
Valeria GaudieriDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, Naples, 80131, Italy.
Adriana D'AntonioDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, Naples, 80131, Italy.
Mariarosaria PanicoInstitute of Biostructure and Bioimaging, CNR, Naples, Italy.
Valeria CantoniDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, Naples, 80131, Italy.
Roberta GreenDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, Naples, 80131, Italy.
Pietro BuongiornoDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, Naples, 80131, Italy.
Mario PetrettaIRCCS Synlab SDN, Diagnostic Imaging, Naples, Italy.
Parthiban ArumugamDepartment of Nuclear Medicine, Central Manchester Foundation Trust, Manchester, UK.
Alberto CuocoloDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, Naples, 80131, Italy.
Wanda AcampaDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, Naples, 80131, Italy. acampa@unina.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe assessed the long-term prognostic value of the combined evaluation coronary atherosclerotic burden, myocardial perfusion coronary and flow capacity (CFC) derived from

methodsWe studied 5285 patients with suspected or known CAD who underwent to stress/rest cardiac

resultsDuring a mean time of 43 ± 26 months, 683 events occurred (13% cumulative event rate, with an AER of 2.9% person-years). The events were 127 (19%) cardiac death, 250 (37%) myocardial infarction and 306 (45%) coronary revascularizations. In patients with previous history of CAD angina, stress TPD, MFR and CFC resulted predictors of events (all P < 0.001). Differently, in patients without CAD diabetes, CAC score ≥ 400, stress TPD ≥ 5%, MFR < 2 and impaired CFC resulted as independent predictors. Weibull analysis showed that patients with known CAD, stress TPD ≥ 5%, MFR < 2 and impaired CFC had the highest probability of events.

conclusionThe combined evaluation of myocardial perfusion and CFC can predict outcome in both patients with and without known CAD.

Indexed as

Coronary Artery DiseaseCoronary CirculationMyocardial Perfusion ImagingPositron Emission Tomography Computed TomographyRubidium RadioisotopesAgedFemaleHumansMaleMiddle AgedPrognosisRubidium-82Rubidium RadioisotopesCoronary flow capacityMyocardial perfusion imagingPositron emission tomographyPrognosis

Identifiers

PMID41699277

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.