Evidence map›Paper›PMID 41699234›Full record

ArticleNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2026

Disinhibition of ventral tegmental area during initial punishment learning causes enduring punishment insensitivity.

Shannen Y S Tan, Michelle H Shen, Luke J Keevers, Matthew Williams-Spooner, Gavan P McNally, Simon Killcross, Philip Jean-Richard-Dit-Bressel

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Brain Architecture of Punishment Learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shannen Y S TanSchool of Psychology, UNSW, Sydney, Australia.
Michelle H ShenSchool of Psychology, UNSW, Sydney, Australia.
Luke J KeeversSchool of Psychology, UNSW, Sydney, Australia.
Matthew Williams-SpoonerSchool of Psychology, UNSW, Sydney, Australia.
Gavan P McNallySchool of Psychology, UNSW, Sydney, Australia.ORCID http://orcid.org/0000-0001-9061-6463
Simon KillcrossSchool of Psychology, UNSW, Sydney, Australia.
Philip Jean-Richard-Dit-BresselSchool of Psychology, UNSW, Sydney, Australia. p.jean-richardditbressel@unsw.edu.au.ORCID http://orcid.org/0000-0002-0898-8987

Funding

Department of Education and Training | Australian Research Council (ARC) DP220100040Department of Education and Training | Australian Research Council (ARC) DP220102317
6 · The paper itself

Abstract

Avoiding actions with negative consequences is fundamental to adaptive behavior. Traditional theories suggest GABAergic inhibition of midbrain dopamine neurons, including those within ventral tegmental area (VTA

Indexed as

Avoidance LearningNeural InhibitionPunishmentVentral Tegmental AreaAnimalsGABA-A Receptor Antagonistsgamma-Aminobutyric AcidMaleRatsReceptors, GABA-AGABA-A Receptor Antagonistsgamma-Aminobutyric AcidReceptors, GABA-A

Identifiers

PMID41699234
PMCPMC13125270

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.