Evidence map›Paper›PMID 41699191›Full record

Articlenpj antimicrobials and resistance2026

Genomic landscape of antimicrobial resistance in India: findings from a multi-species surveillance study.

Nazneen Gheewalla, Vasundhara Karthikeyan, Yuvraj Jadhav, Kirti Kulkarni, Akansha Tyagi, Jaisri Jagannadham, Sandeep Budhiraja, Bansidhar Tarai, Maithili Kavathekar, Shraddha Karve

Abstract read
In one paragraph

Article in npj antimicrobials and resistance, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nazneen GheewallaTrivedi School of Biosciences, Ashoka University, Sonipat, India.
Vasundhara KarthikeyanTrivedi School of Biosciences, Ashoka University, Sonipat, India.
Yuvraj JadhavTrivedi School of Biosciences, Ashoka University, Sonipat, India.
Kirti KulkarniSahyadri Hospitals Pvt Ltd, Pune, Maharashtra, India.
Akansha TyagiMax Super Speciality Hospital (A unit of Devki Devi Foundation), Saket, New Delhi, India.
Jaisri JagannadhamTrivedi School of Biosciences, Ashoka University, Sonipat, India.
Sandeep BudhirajaInstitute of Internal Medicine, Max Super Speciality Hospital (A unit of Devki Devi Foundation), Saket, New Delhi, India.
Bansidhar TaraiMax Healthcare, New Delhi, India.
Maithili KavathekarSahyadri Hospitals Pvt Ltd, Pune, Maharashtra, India.
Shraddha KarveTrivedi School of Biosciences, Ashoka University, Sonipat, India. shraddha.karve@ashoka.edu.in.

Funding

Rockefeller Foundation 2021 HTH 018
6 · The paper itself

Abstract

Antimicrobial resistance (AMR) is a major public health threat, especially in low- and middle-income countries (LMICs), where large datasets linking antimicrobial susceptibility testing (AST) with genomic data remain limited. We analyzed AST results and whole genomes from 266 resistant bacterial isolates representing diverse species and specimen sources, collected from Northern and Western India between 2022 and 2024. Correlation of genomic resistance predictions with AST data revealed an overprediction of resistance by genomic methods. To our knowledge, this is the first study to systematically examine these discrepancies across multiple antibiotic-pathogen combinations in India and to identify promising targets for genomic resistance prediction. We also investigated the predominant antibiotic resistance genes (ARGs), plasmids, and other mobile genetic elements associated with them. Overall, our findings contribute meaningfully to the genomic epidemiology of AMR in India and support the development of molecular diagnostics for antimicrobial resistance.

Identifiers

PMID41699191
PMCPMC12910060

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.