Evidence map›Paper›PMID 41699169›Full record

ArticleScientific reports2026

DGOU classification guided cement diffusion strategy in unilateral kyphoplasty for osteoporotic vertebral compression fractures.

Donghui Cao, Xusheng Li, Wenbo Gu, Yanrong Tian, Yu Yang, Zhe Liu, Xiao Zhang, Hanlin Zhang, Haiqiang Ma, Hongyang Zhao and 6 more

Abstract readMulticenter Study
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Donghui Cao *Department of Spinal Orthopedics, General Hospital of Ningxia Medical University, Ningxia Hui Autonomous Region, Yinchuan, China.ORCID http://orcid.org/0009-0000-5038-2279
Xusheng Li *Department of Spinal Orthopedics, General Hospital of Ningxia Medical University, Ningxia Hui Autonomous Region, Yinchuan, China.
Wenbo GuDepartment of Spinal Orthopedics, General Hospital of Ningxia Medical University, Ningxia Hui Autonomous Region, Yinchuan, China.
Yanrong TianDepartment of Spinal Orthopedics, General Hospital of Ningxia Medical University, Ningxia Hui Autonomous Region, Yinchuan, China.
Yu YangDepartment of Spinal Orthopedics, General Hospital of Ningxia Medical University, Ningxia Hui Autonomous Region, Yinchuan, China.
Zhe LiuDepartment of Spinal Orthopedics, General Hospital of Ningxia Medical University, Ningxia Hui Autonomous Region, Yinchuan, China.
Xiao ZhangDepartment of Spinal Orthopedics, General Hospital of Ningxia Medical University, Ningxia Hui Autonomous Region, Yinchuan, China.
Hanlin ZhangOrthopedics Department, People's Hospital of Ningxia Hui Autonomous Region, Ningxia Hui Autonomous Region, Yinchuan, China.
Haiqiang MaOrthopedics Department, The Third People's Hospital of Yinchuan City, Ningxia Hui Autonomous Region, Yinchuan, China.
Hongyang ZhaoDepartment of Spinal Orthopedics, Qinghai University Affiliated Hospital, Xining, Qinghai Province, China.
Binjie FanDepartment of Spinal Orthopedics, General Hospital of Ningxia Medical University, Ningxia Hui Autonomous Region, Yinchuan, China.
Tengyao NiuDepartment of Spinal Orthopedics, General Hospital of Ningxia Medical University, Ningxia Hui Autonomous Region, Yinchuan, China.
Yulong NanDepartment of Spinal Orthopedics, General Hospital of Ningxia Medical University, Ningxia Hui Autonomous Region, Yinchuan, China.
Pengcheng MaoDepartment of Spinal Orthopedics, General Hospital of Ningxia Medical University, Ningxia Hui Autonomous Region, Yinchuan, China.
Xi ZhuDepartment of Spinal Orthopedics, General Hospital of Ningxia Medical University, Ningxia Hui Autonomous Region, Yinchuan, China. zx_830724@163.com.
Haifeng YuanDepartment of Spinal Orthopedics, General Hospital of Ningxia Medical University, Ningxia Hui Autonomous Region, Yinchuan, China. yuan18709571510@163.com.ORCID http://orcid.org/0000-0002-2042-1748

Funding

Key Research and Development Program of Ningxia 2024BEH04159Natural Science Foundation of Ningxia Province 2023AAC03543Natural Science Foundation of Ningxia Province 2024AAC05082Natural Science Foundation of Ningxia Province 2025AAC030812
6 · The paper itself

Abstract

The optimal cement diffusion pattern in unilateral percutaneous kyphoplasty (PKP) for osteoporotic vertebral compression fractures (OVCFs) remains debated. This multicenter retrospective study investigated whether crossing the vertebral midline with bone cement is necessary under the DGOU classification. A total of 440 patients with single-level OVCFs treated by unilateral PKP (2020-2023) were categorized into OF1, OF2, or OF3 types based on the DGOU classification and further divided into crossing and non-crossing groups according to postoperative CT. Outcomes included VAS, ODI, and radiographic parameters. In OF1 fractures, no significant differences were observed between the two groups. However, for OF2 and OF3 fractures, the crossing group demonstrated significantly better ODI scores at 6 and 12 months (P < 0.001) and improved vertebral height maintenance (P < 0.001), without increasing complications. These findings suggest that achieving cross-midline cement diffusion may not be necessary for stable OF1 fractures, but it is associated with significantly better mid- to long-term functional and radiographic outcomes in unstable OF2/OF3 fracture types.

Indexed as

Bone CementsFractures, CompressionKyphoplastyOsteoporotic FracturesSpinal FracturesAgedAged, 80 and overFemaleHumansMaleRetrospective StudiesTreatment OutcomeBone CementsBone cement diffusionDGOU classificationMidlineOsteoporotic vertebral compression fracturePercutaneous kyphoplastyUnilateral puncture

Identifiers

PMID41699169
PMCPMC13000226

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.