Evidence map›Paper›PMID 41699153›Full record

ArticleScientific reports2026

Dysregulation of Endothelial cell markers in polycystic ovary syndrome.

Preeti Borde, Sara Anjum Niinuma, Haniya Habib, Ashleigh Suzu-Nishio Takemoto, Manjula Nandakumar, Thozhukat Sathyapalan, Alexandra E Butler, Stephen L Atkin

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Preeti BordeRoyal College of Surgeons in Ireland Bahrain, Adliya, 15503, Kingdom of Bahrain.
Sara Anjum NiinumaRoyal College of Surgeons in Ireland Bahrain, Adliya, 15503, Kingdom of Bahrain.
Haniya HabibRoyal College of Surgeons in Ireland Bahrain, Adliya, 15503, Kingdom of Bahrain.
Ashleigh Suzu-Nishio TakemotoRoyal College of Surgeons in Ireland Bahrain, Adliya, 15503, Kingdom of Bahrain.
Manjula NandakumarRoyal College of Surgeons in Ireland Bahrain, Adliya, 15503, Kingdom of Bahrain.
Thozhukat SathyapalanAcademic Endocrinology, Diabetes and Metabolism, Hull York Medical School, Hull, UK.
Alexandra E Butler *Royal College of Surgeons in Ireland Bahrain, Adliya, 15503, Kingdom of Bahrain. aeb91011@gmail.com.
Stephen L Atkin *Royal College of Surgeons in Ireland Bahrain, Adliya, 15503, Kingdom of Bahrain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endothelial cell dysfunction is reported to occur in polycystic ovary syndrome (PCOS) but it is unclear if this is due to obesity or inherent to PCOS. We hypothesized that in body mass index (BMI)-matched women with obesity, with and without PCOS, endothelial cell dysfunction protein markers would differ due to the inherent pathophysiology of PCOS. 92 women with PCOS and 19 control subjects were identified from a PCOS and control biobank and matched for obesity (BMI ≥ 30 kg/m

Indexed as

BiomarkersEndothelial CellsPolycystic Ovary SyndromeAdultBody Mass IndexCase-Control StudiesC-Reactive ProteinFemaleFibrin Fibrinogen Degradation ProductsHumansInsulin ResistanceIntercellular Adhesion Molecule-1ObesityPlasminogen Activator Inhibitor 1Tissue Plasminogen ActivatorBiomarkersC-Reactive ProteinFibrin Fibrinogen Degradation Productsfibrin fragment DIntercellular Adhesion Molecule-1Plasminogen Activator Inhibitor 1SERPINE1 protein, humanTissue Plasminogen ActivatorD-DimerEndothelial cell markersICAM-1PAI-1Polycystic ovary syndromeTissue plasminogen activator

Identifiers

PMID41699153
PMCPMC13000210

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.