Evidence map›Paper›PMID 41699090›Full record

Observational studyJournal of perinatology : official journal of the California Perinatal Association2026

Wide variation in death rates and post-hemorrhagic hydrocephalus (PHH) treatment in preterm severe intraventricular hemorrhage (IVH).

Kelly B Mahaney, Arokoruba Cheetham-West, Xin Cui, Jessica Liu, Gerald A Grant, Jochen Profit

Abstract readObservational Study
In one paragraph

Observational study in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kelly B MahaneyStanford University Department of Neurosurgery, Division of Pediatric Neurosurgery, Palo Alto, CA, USA. kmahaney@stanford.edu.ORCID http://orcid.org/0000-0001-8387-7868
Arokoruba Cheetham-WestStanford University Department of Neurosurgery, Division of Pediatric Neurosurgery, Palo Alto, CA, USA.
Xin CuiCalifornia Perinatal Quality Care Collaborative, Palo Alto, CA, USA.ORCID http://orcid.org/0000-0002-4277-7972
Jessica LiuCalifornia Perinatal Quality Care Collaborative, Palo Alto, CA, USA.
Gerald A GrantStanford University Department of Neurosurgery, Division of Pediatric Neurosurgery, Palo Alto, CA, USA.
Jochen ProfitCalifornia Perinatal Quality Care Collaborative, Palo Alto, CA, USA.ORCID http://orcid.org/0000-0002-3782-9248

Funding

Institutional Career Development Core (KL2)KL2TR003143 · NCATS · STANFORD UNIVERSITY · PI ASCH, STEVEN M. · 2019 to 2023
$8.7M
A Dashboard of Racial/Ethnic Disparity in Care Provided by NICUsR01HD083368 · NICHD · STANFORD UNIVERSITY · PI PROFIT, JOCHEN · 2016 to 2020
$3.2M
U.S. Department of Health & Human Services | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) R01HD083368U.S. Department of Health & Human Services | NIH | NIH Clinical Center (Clinical Center) KL2TR003143
6 · The paper itself

Abstract

objectiveDetermine if decreased rates of severe IVH in VLBW infants in California translated to decreased rates of infant death or PHH treatment among those with severe IVH, and to evaluate variations in neurosurgical treatment of neonatal PHH. STUDY

designRetrospective observational cohort study of infants with severe IVH (grade III or IV) born at 22

resultSevere IVH rates declined in California with a concurrent decline in PHH treatment or infant death. Regional variability was observed in PHH treatment or infant death (range 38.0-55.9%, p < 0.0001) and the rates of utilizing a "shunt-first" PHH-treatment approach (range 25.5-81.5%, p < 0.0001).

conclusionThere is striking regional variation in the neurosurgical management of neonatal PHH and thus an urgent need to adopt standardized practices in IVH management.

Indexed as

Cerebral HemorrhageCerebral Intraventricular HemorrhageHydrocephalusInfant, Premature, DiseasesCaliforniaFemaleGestational AgeHumansInfant MortalityInfant, NewbornInfant, PrematureInfant, Very Low Birth WeightMaleRetrospective Studies

Identifiers

PMID41699090
PMCPMC13290465

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.