Evidence map›Paper›PMID 41699089›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2026

Results of a pulmonary hypertension screening program for premature infants with bronchopulmonary dysplasia.

Ramya Ramachandra, Alisa Arunamata, Amanda Moy, Michael C Tracy, Yinyao Ji, Derek Boothroyd, Rachel K Hopper

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Article in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ramya RamachandraDivision of Pediatric Cardiology, Department of Pediatrics, Stanford University School of Medicine, Lucile Packard Children's Hospital Stanford, Palo Alto, CA, USA.
Alisa ArunamataDivision of Pediatric Cardiology, Department of Pediatrics, Stanford University School of Medicine, Lucile Packard Children's Hospital Stanford, Palo Alto, CA, USA.
Amanda MoyDivision of Neonatology, Department of Pediatrics, Stanford University School of Medicine, Lucile Packard Children's Hospital Stanford, Palo Alto, CA, USA.
Michael C TracyDivision of Pulmonary Medicine, Department of Pediatrics, Stanford University School of Medicine, Lucile Packard Children's Hospital Stanford, Palo Alto, CA, USA.
Yinyao JiQuantitative Sciences Unit, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0002-5548-2508
Derek BoothroydQuantitative Sciences Unit, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Rachel K HopperDivision of Pediatric Cardiology, Department of Pediatrics, Stanford University School of Medicine, Lucile Packard Children's Hospital Stanford, Palo Alto, CA, USA. rhopper@stanford.edu.ORCID http://orcid.org/0000-0002-7483-2825

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePremature infants with bronchopulmonary dysplasia (BPD) are at risk for pulmonary hypertension (PH). We sought to evaluate outcomes of a PH screening protocol. STUDY

designSingle-center retrospective cohort study of premature infants with ≥moderate BPD from 6/2017 to 11/2022 subject to an institutional PH screening protocol that included echocardiogram and serum N-terminal pro B-type natriuretic peptide (NT-proBNP) levels measured at 36 weeks postmenstrual age.

resultScreening echocardiography detected PH in 15% (95% CI 10.0%, 22.1%). Multivariate analysis identified an association between lower gestational age and incidence of PH. There was no difference in right ventricular systolic function metrics among infants with PH compared to those without. Sensitivity and specificity of serum NT-proBNP were 57% and 45%, respectively.

conclusionEchocardiographic screening can detect unrecognized PH in infants before significant decrement of right ventricular performance, while serum NT-proBNP may not be a reliable screening tool for PH in infants with BPD.

Identifiers

PMID41699089

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.