ArticleScientific reports2026
The efficacy of rimegepant for the acute treatment of vestibular migraine.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Vestibular Migraine: A Systematic Literature Search and Narrative Review of Diagnostic Criteria, Pathophysiology, Differential Diagnosis, and Treatment Approaches.Medeniyet medical journal · 2026Article
- Innovations in conservative and surgical therapy for Ménière's disease-narrative review.Frontiers in neurologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
introductionThis study aimed to observe the efficacy and safety of rimegepant, a small-molecule calcitonin gene-related peptide (CGRP) receptor antagonist, for the acute treatment of vestibular migraine (VM).
methodsPatients meeting the diagnostic criteria for VM or probable VM received rimegepant 75 mg for acute attacks. They rated the severity of five prominent VM symptoms (vertigo, unsteadiness or dizziness, nausea or vomiting, photophobia or phonophobia, and headache) on a 0-3 scale. Assessments were recorded at baseline, 30 min, 1 h, 2 h, 4 h, 24 h, and 48 h post-treatment. Efficacy outcomes included the percentage of patients with symptom recovery (from moderate/severe to absent/mild), moderate/severe symptoms, and freedom from symptoms at various time points.
results18 VM patients were included. All symptom scores showed a decreasing trend from 30 min after rimegepant treatment. Scores for all symptoms except headache were significantly decreased at 2 h. The percentage of patients with moderate/severe symptoms decreased from 50.0% to 72.2% at baseline to 0% by 24 h for all symptoms. Moreover, freedom from all symptoms except unsteadiness/dizziness was achieved by 24 h. No adverse events were reported.
conclusionWe first demonstrate rimegepant 75 mg is safe and well-tolerated, which contributes a rapid relief of the prominent symptoms of VM including vertigo, unsteadiness or dizziness, nausea or vomiting, photophobia or phonophobia, and headache. Although required further validation, our findings may provide novel viewpoint on the treatment of VM.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.