ArticleJournal of animal science2026
Effects of spray-dried animal plasma on inflammatory indicators, antioxidant capacity, and joint health in senior dogs.
Article in Journal of animal science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Osteoarthritis (OA) is a chronic progressive degeneration joint disorder influenced by risk factors, such as genetics, age, and obesity. The purpose of this study was to investigate the effects of spray-dried animal plasma (SDAP) on nutrient digestibility, inflammatory responses, antioxidant capacity, and joint health in senior dogs with OA. Twenty-four dogs over 7 years old diagnosed with OA based on radiographic evidence and clinical signs were randomly assigned to 2 groups with 12 replicates per group. The following dietary treatments were administered: 1) CONTROL group: dogs with OA were provided a basal diet; 2) SDAP group: dogs with OA were provided a basal diet supplemented with 4% SDAP replacing chicken meal. The feeding trial lasted 42 days. This study found that the total tract apparent digestibility of crude protein was improved in the SDAP group compared to the CONTROL group (P < 0.05). Regarding antioxidant status, serum superoxide dismutase levels were increased, whereas malondialdehyde levels were decreased in the SDAP group compared to the CONTROL group on days 21 and 42 (P < 0.05). On d 42, serum interleukin-1β and metalloproteinase-13 levels in the SDAP group were significantly decreased compared to the CONTROL group (P < 0.05), alongside higher levels of serum interleukin-10 in the SDAP group (P < 0.05). Additionally, synovial fluid metalloproteinase-2 levels were significantly reduced in the SDAP group compared to the CONTROL group on day 42 (P < 0.05). Clinically, the lameness scores were significantly reduced in the SDAP group on day 42 relative to the CONTROL group (P < 0.05), indicating an alleviation of arthritis symptoms in dogs of the SDAP group. In conclusion, dietary supplementation with 4% SDAP could increase protein digestibility, alleviate inflammatory response, improve antioxidant properties, and relieve canine arthritis symptoms in senior dogs with OA. These findings support SDAP as a promising dietary intervention strategy for managing joint health in senior dogs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.