Evidence map›Paper›PMID 41697605›Full record

SynthesisUpdates in surgery2026

A systematic review on surgical trends after ileal pouch-anal anastomosis for inflammatory bowel disease: shifting the focus from traditional to minimally invasive approaches.

Gaetano Gallo, Stefano Agnesi, Silvio Danese, Andrea Vignali, Ileal Pouch-Anal Anastomosis Working Group, Pierpaolo Sileri

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Updates in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gaetano GalloColorectal Surgery Unit, IRCCS San Raffaele Scientific Institute, Vita-Salute University, Via Olgettina 60, 20132, Milan, Italy. gallo.gaetano@hsr.it.ORCID http://orcid.org/0000-0003-1066-4671
Stefano AgnesiColorectal Surgery Unit, IRCCS San Raffaele Scientific Institute, Vita-Salute University, Via Olgettina 60, 20132, Milan, Italy.ORCID http://orcid.org/0000-0002-7472-2669
Silvio DaneseDepartment of Gastroenterology and Endoscopy, IRCCS San Raffaele Scientific Institute, Vita-Salute University, Via Olgettina 60, 20132, Milan, Italy.
Andrea VignaliColorectal Surgery Unit, IRCCS San Raffaele Scientific Institute, Vita-Salute University, Via Olgettina 60, 20132, Milan, Italy.
Ileal Pouch-Anal Anastomosis Working Group
Pierpaolo SileriColorectal Surgery Unit, IRCCS San Raffaele Scientific Institute, Vita-Salute University, Via Olgettina 60, 20132, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ileal pouch-anal anastomosis (IPAA) has been the preferred surgical treatment for selected patients with inflammatory bowel disease (IBD) since its introduction in 1978. Over the past 3 decades, significant advances have occurred, particularly with the evolution of minimally invasive surgical techniques. This systematic review aimed to analyze surgical outcomes following IPAA over the last 30 years, focusing on the transition from open to minimally invasive approaches. A comprehensive search was conducted in PubMed, Embase, and Web of Science, yielding 46,024 articles. Studies were categorized into three time periods: Group A (1980-1999), Group B (2000-2009), and Group C (2010-2025). The review was registered in PROSPERO (CRD42024604869). Twenty studies published between 1981 and 2018 were included, encompassing a total of 5474 patients. Group A comprised 3903 patients (71.3%), Group B 1312 (24.0%), and Group C 259 (4.7%). Use of laparoscopic approaches increased substantially over time: 11.9% in Group A, 26.2% in Group B, and 54.4% in Group C. Conversely, the rate of diverting loop ileostomy decreased from 88.6% in Group A to 69.9% in Group B and 23.8% in Group C. The proportion of patients undergoing concomitant proctocolectomy at the time of IPAA declined markedly from 93.1% (Group A) to 38.4% (Group B) and 22% (Group C). Length of hospital stay progressively decreased, with mean durations of 11.9 ± 2.6 days, 11.0 ± 5.4 days, and 7.8 ± 2.7 days in Groups A, B, and C, respectively. Postoperative complication rates also declined significantly: 86.7% in Group A, 66.8% in Group B, and 37.8% in Group C. Over the last three decades, surgical outcomes following IPAA for IBD have markedly improved. This improvement coincides with an increased use of minimally invasive techniques and a shift toward staged surgical approaches.

Indexed as

Colonic PouchesInflammatory Bowel DiseasesLaparoscopyMinimally Invasive Surgical ProceduresProctocolectomy, RestorativeAnastomosis, SurgicalHumansTreatment OutcomeIleal J pouchIleal pouch-anal anastomosis (IPAA)Ileoanal anastomosisJ-pouchPouch

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.