Evidence map›Paper›PMID 41697566›Full record

Trial reportAIDS and behavior2026

Acceptability of an Integrated Model of Mental Health and PrEP Service Delivery for South African Adolescent Girls: Qualitative Results from a Pilot Hybrid Effectiveness-Implementation Randomized Trial.

Lisa Mills, Sinead Delany-Moretlwe, Makhosazane Nomhle Ndimande-Khoza, Hlukelo Chauke, Nikita Govender, Nicole Poovan, Ruth Verhey, Dixon Chibanda, Connie Celum, Jennifer Velloza

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in AIDS and behavior, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lisa MillsWits RHI, Faculty of Health Sciences, University of Witwatersrand, 22 Esselen Street, Johannesburg, 2000, Republic of South Africa. lmills@wrhi.ac.za.ORCID http://orcid.org/0000-0002-6168-7008
Sinead Delany-MoretlweWits RHI, Faculty of Health Sciences, University of Witwatersrand, 22 Esselen Street, Johannesburg, 2000, Republic of South Africa.
Makhosazane Nomhle Ndimande-KhozaWits RHI, Faculty of Health Sciences, University of Witwatersrand, 22 Esselen Street, Johannesburg, 2000, Republic of South Africa.
Hlukelo ChaukeWits RHI, Faculty of Health Sciences, University of Witwatersrand, 22 Esselen Street, Johannesburg, 2000, Republic of South Africa.
Nikita GovenderWits RHI, Faculty of Health Sciences, University of Witwatersrand, 22 Esselen Street, Johannesburg, 2000, Republic of South Africa.
Nicole PoovanWits RHI, Faculty of Health Sciences, University of Witwatersrand, 22 Esselen Street, Johannesburg, 2000, Republic of South Africa.
Ruth VerheyFriendship Bench Program, Harare, Zimbabwe.
Dixon ChibandaFriendship Bench Program, Harare, Zimbabwe.
Connie CelumDepartment of Global Health, University of Washington, Seattle, WA, USA.
Jennifer VellozaDepartment of Epidemiology & Biostatistics, University of California San Francisco, San Francisco, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adolescent girls and young women (AGYW) at elevated HIV risk often experience common mental disorders (CMD), which are linked to lower PrEP adherence. We piloted a CMD intervention, the Youth Friendship Bench SA (YFB), and delivered alongside PrEP to improve CMD symptoms and PrEP adherence among South African AGYW. From April 2023-February 2024, 116 AGYW (18-25 years) with CMD symptoms were randomized to YFB plus standard of care (SOC) or SOC alone and followed for 12 weeks. In-depth interviews were conducted with 30 AGYW and 13 study staff and key informants. CMD screening alone was seen as beneficial, but referral uptake was low due to perceived severity thresholds, staff attitudes, and logistical barriers. YFB was highly acceptable to AGYW, who valued the intervention for being confidential, informal, and empowering. Integrated CMD and PrEP services were acceptable, and lay counsellor delivery shows promise for addressing the mental health care gap.

Indexed as

Anti-HIV AgentsHIV InfectionsMental DisordersPatient Acceptance of Health CarePre-Exposure ProphylaxisAdherence InterventionsAdolescentAdultFemaleHumansMedication AdherenceMental HealthMental Health ServicesPilot ProjectsQualitative ResearchSouth AfricaAnti-HIV AgentsAcceptabilityAdolescent girls and young womenHIVHybrid trialMental healthPre-exposure prophylaxis

Identifiers

PMID41697566
PMCPMC13303429

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.