Evidence map›Paper›PMID 41697538›Full record

ArticleClinical journal of gastroenterology2026

Gastrointestinal-localized polymorphic post-transplant lymphoproliferative disorder following kidney transplantation after allogeneic hematopoietic stem cell transplantation: a rare case report.

Yoshiki Morihisa, Satoko Inoue, Kohei Uyama, Shotaro Ueno, Takanari Minoshima, Soichiro Nagao, Yohei Yabuuchi, Shigeo Hara, Naoki Kanda

Abstract readCase Reports
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In one paragraph

Article in Clinical journal of gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Yoshiki MorihisaDepartment of Gastroenterology, Kobe City Medical Center General Hospital, 2-1-1, Minatojimaminami-machi, Chuo-ku, Kobe, Hyogo, 650-0047, Japan.
Satoko InoueDepartment of Gastroenterology, Kobe City Medical Center General Hospital, 2-1-1, Minatojimaminami-machi, Chuo-ku, Kobe, Hyogo, 650-0047, Japan. satoin@kcho.jp.ORCID http://orcid.org/0009-0006-9476-466X
Kohei UyamaDepartment of Gastroenterology, Kobe City Medical Center General Hospital, 2-1-1, Minatojimaminami-machi, Chuo-ku, Kobe, Hyogo, 650-0047, Japan.
Shotaro UenoDepartment of Gastroenterology, Kobe City Medical Center General Hospital, 2-1-1, Minatojimaminami-machi, Chuo-ku, Kobe, Hyogo, 650-0047, Japan.
Takanari MinoshimaDepartment of Gastroenterology, Kobe City Medical Center General Hospital, 2-1-1, Minatojimaminami-machi, Chuo-ku, Kobe, Hyogo, 650-0047, Japan.
Soichiro NagaoDepartment of Gastroenterology, Kobe City Medical Center General Hospital, 2-1-1, Minatojimaminami-machi, Chuo-ku, Kobe, Hyogo, 650-0047, Japan.
Yohei YabuuchiDepartment of Gastroenterology, Kobe City Medical Center General Hospital, 2-1-1, Minatojimaminami-machi, Chuo-ku, Kobe, Hyogo, 650-0047, Japan.
Shigeo HaraDepartment of Pathology, Kobe City Medical Center General Hospital, Kobe, Japan.
Naoki KandaDepartment of Gastroenterology, Kobe City Medical Center General Hospital, 2-1-1, Minatojimaminami-machi, Chuo-ku, Kobe, Hyogo, 650-0047, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post-transplant lymphoproliferative disorder (PTLD) is an uncommon but potentially life-threatening complication of solid organ transplantation (SOT) or hematopoietic stem cell transplantation (HSCT). Therefore, early diagnosis and appropriate treatment are crucial. We report a case of a 37-year-old male who developed gastrointestinal-localized Epstein-Barr Virus (EBV)-associated polymorphic PTLD 5 months after kidney transplantation for diabetic nephropathy. The patient had undergone allogeneic HSCT (allo-HSCT) for acute myeloid leukemia 14 years prior and developed chronic graft-versus-host disease and secondary hypogammaglobulinemia. A reduction in immunosuppressive therapy was insufficient to control the PTLD, and the patient achieved complete remission with rituximab monotherapy. To the best of our knowledge, a case of early onset PTLD following SOT after allo-HSCT has not been previously reported. This case highlights that PTLD can develop in patients with prolonged or compounded immunosuppression and emphasizes the importance of PTLD recognition and appropriate diagnosis and management.

Indexed as

Epstein-Barr Virus InfectionsGastrointestinal DiseasesHematopoietic Stem Cell TransplantationKidney TransplantationLymphoproliferative DisordersAdultHumansImmunosuppressive AgentsMaleRituximabTransplantation, HomologousImmunosuppressive AgentsRituximabEpstein–Barr virusGastrointestinal ulcerOrgan transplantationPost-transplant lymphoproliferative disorderRituximab

Identifiers

PMID41697538

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.