Evidence map›Paper›PMID 41697481›Full record

ArticleThe Saudi dental journal2026

Metastatic neck involvement in oral squamous cell carcinoma: A retrospective clinicopathological study.

Medyan Al Rousan, Ra'ad Alsunna, Lamees AlKhalili, Jowan Al-Nusair, Raya Manasrah, Sumaiah H AlNaimat, Raed Dwaik, Lina Alelaumi, Jareer Shatnawi

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Article in The Saudi dental journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Medyan Al RousanKing Hussein Cancer Center (KHCC), P.O. Box 1269, Al-Jubeiha, Amman, 11941, Jordan.
Ra'ad AlsunnaKing Hussein Cancer Center (KHCC), P.O. Box 1269, Al-Jubeiha, Amman, 11941, Jordan.
Lamees AlKhaliliKing Hussein Cancer Center (KHCC), P.O. Box 1269, Al-Jubeiha, Amman, 11941, Jordan. lameesalkhalili@hotmail.com.ORCID http://orcid.org/0009-0004-3920-2045
Jowan Al-NusairDepartment of Internal Medicine, Marshall University Joan C. Edwards School of Medicine, Huntington, WV, 25701, USA.
Raya ManasrahKing Hussein Cancer Center (KHCC), P.O. Box 1269, Al-Jubeiha, Amman, 11941, Jordan.
Sumaiah H AlNaimatKing Hussein Cancer Center (KHCC), P.O. Box 1269, Al-Jubeiha, Amman, 11941, Jordan.
Raed DwaikKing Hussein Cancer Center (KHCC), P.O. Box 1269, Al-Jubeiha, Amman, 11941, Jordan.
Lina AlelaumiKing Hussein Cancer Center (KHCC), P.O. Box 1269, Al-Jubeiha, Amman, 11941, Jordan.
Jareer ShatnawiKing Hussein Cancer Center (KHCC), P.O. Box 1269, Al-Jubeiha, Amman, 11941, Jordan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral squamous cell carcinoma (OSCC) is the most common oral malignancy, with neck metastasis significantly affecting prognosis and treatment. This study examines clinicopathological factors associated with neck metastasis in a Middle Eastern cohort of OSCC patients. A retrospective analysis of 84 OSCC patients treated at King Hussein Cancer Center (2018-2024) was conducted. Clinicopathological factors, including tumor subsite, T stage, depth of invasion, differentiation, perineural invasion, and lymphovascular invasion were evaluated for their association with lymph node metastasis. Pathological neck involvement was observed in 47.6% of cases. Late T stage (T3-T4) and LVI positivity were identified as independent predictors of nodal metastasis (aOR = 4.25, p = 0.009; aOR = 4.39, p = 0.027, respectively). These findings highlight the importance of comprehensive pathological assessment in OSCC.

Indexed as

Lymph nodeNeck involvementOral squamous cell carcinomaRetrospective

Identifiers

PMID41697481
PMCPMC12909653

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.