Evidence map›Paper›PMID 41697453›Full record

ReviewOphthalmology and therapy2026

Management of Thyroid Eye Disease: A Comparison Between Three Recent Clinical Guidelines.

Chaoyu Lei, Jun Jin, Runchuan Li, Chee Chew Yip, Kelvin Kam Lung Chong, Terry J Smith, Jing Sun, Huifang Zhou

Abstract readReview
In one paragraph

Review in Ophthalmology and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chaoyu Lei *State Key Laboratory of Eye Health, Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jun Jin *State Key Laboratory of Eye Health, Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Runchuan LiState Key Laboratory of Eye Health, Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Chee Chew YipDepartment of Ophthalmology & Visual Sciences, Khoo Teck Puat Hospital, Singapore, Singapore.
Kelvin Kam Lung ChongDepartment of Ophthalmology and Visual Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
Terry J SmithDepartment of Ophthalmology and Visual Sciences, Kellogg Eye Center, Ann Arbor, MI, USA.
Jing SunState Key Laboratory of Eye Health, Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. sophiasj@126.com.
Huifang ZhouState Key Laboratory of Eye Health, Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. fangzzfang@sjtu.edu.cn.ORCID http://orcid.org/0000-0002-8636-861X

Funding

Hainan Province Science and Technology Special Fund ZDYF2024LCLH004National Key R&D Program of China 2024YFB4710200National Key R&D Program of China 2024YFB4710205National Natural Science Foundation of China 82271122National Natural Science Foundation of China 82388101Science and Technology Commission of Shanghai Municipality 20DZ2270800Shanghai Jiao Tong University 2030 Initiative WH510272301Shanghai Jiao Tong University Hainan Institute's Independent Research Initiative HRSJ-ZSZX-009Shanghai Key Clinical Specialty, Shanghai Eye Disease Research Center 2022ZZ01003Shanghai Municipal Commission of Health and Family Planning Project 2022XD006Shanghai Three-Year Plan for the Inheritance and Innovative Development of Traditional Chinese Medicine 2-5-1
6 · The paper itself

Abstract

Rapid advances in the diagnosis and treatment of thyroid eye disease (TED) have led to the development of three patient care guidelines by regional professional societies: the European Group on Graves' Orbitopathy, the Oculoplastics and Orbital Diseases Group of the Chinese Medical Association Ophthalmology Branch/Thyroid Group of the Chinese Medical Association Endocrinology Branch, and the American Thyroid Association/European Thyroid Association. Although broad consensus can be found across the three guidelines, important differences could affect patient management. This review examines and compares the recommendations of these guidelines across 11 dimensions, from disease diagnosis to treatment strategies. We explore the possible root sources of these variations. The review also suggests future directions and potential implications, thus providing a comprehensive perspective of current and future management of TED.

Indexed as

ComparisonConsensus statementGuidelineThyroid eye disease

Identifiers

PMID41697453
PMCPMC12976230

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.