ArticleEuropean journal of nutrition2026
Magnesium supplements, sleep quality, and nocturnal leg cramps: a combination of cross-sectional and prospective studies.
Article in European journal of nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Nutritional adaptation to circadian misalignment: implications for musculoskeletal health in modern lifestyles.Frontiers in nutrition · 2026Review
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Authors and funding
3 authors.
Funding
Abstract
purposeMany individuals turn to supplements like magnesium, believing them to offer a natural way to improve sleep quality. Yet, research on magnesium’s effects has produced inconsistent results. We assessed the relationships between magnesium supplementation and subjective/ or objective sleep parameters, including night cramps.
methodsData from three follow-ups of the population based CoLaus|PsyColaus cohort: 2009–12 (first), 2014–17 (second), and 2018–21 (third). Magnesium supplement use was self-reported, and participants were categorized either as users or non-users. Subjective sleep parameters were measured through questionnaires, and objective sleep parameters with polysomnography. The researchers computed a polygenic risk score (PRS) including five single nucleotide polymorphisms related to magnesium levels.
resultsThe number and characteristics of the participants in the first, second, and third follow-ups were 3887 (52.6% women, 57.2 ± 10.4 years, 4.5% magnesium users), 1916 (49.7% women, 60.8 ± 9.4 years, 7.9% users), and 1561 (51.2% women, 63.1 ± 8.9 years, 7.5% users), respectively. The multivariable-adjusted analyses indicated that magnesium users had a higher likelihood of experiencing night cramps or restless leg syndrome, with a trend towards poorer sleep quality. Multivariable-adjusted analyses revealed no significant differences between participants with and without cramps regarding polysomnography results or magnesium PRS. The prospective analyses demonstrated that participants taking magnesium supplements at baseline had a higher incidence of night cramps. The incidence of restless leg syndrome did not differ between users and non-users.
conclusionWe found no consistent association between magnesium supplementation and subjective or objective sleep parameters or restless leg syndrome. Magnesium supplementation did not prevent night cramps.
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