The effect of bile salts stress on the biology and transcriptome characteristics of Vibrio parahaemolyticus under low salt environment.

Zhiyong Song, Ran Zhang, Shiying Ji, Zhengchuan Long, Yingjie Pan, Qingchao Xie, Yong Zhao, Haiquan Liu

Abstract read

In one paragraph

Article in Archives of microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhiyong Song *College of Food Science and Technology, Shanghai Ocean University, Shanghai, 201306, China.

Ran Zhang *College of Food Science and Technology, Shanghai Ocean University, Shanghai, 201306, China.

Shiying JiCollege of Food Science and Technology, Shanghai Ocean University, Shanghai, 201306, China.

Zhengchuan LongCollege of Food Science and Technology, Shanghai Ocean University, Shanghai, 201306, China.

Yingjie PanCollege of Food Science and Technology, Shanghai Ocean University, Shanghai, 201306, China.

Qingchao XieCollege of Food Science and Technology, Shanghai Ocean University, Shanghai, 201306, China.

Yong ZhaoCollege of Food Science and Technology, Shanghai Ocean University, Shanghai, 201306, China. yzhao@shou.edu.cn.

Haiquan LiuCollege of Food Science and Technology, Shanghai Ocean University, Shanghai, 201306, China. hqliu@shou.edu.cn.

Funding

Shanghai Municipal Science and Technology Committee of Shanghai outstanding academic leaders plan 21XD1401200

6 · The paper itself

Abstract

Vibrio parahaemolyticus is a foodborne pathogen that can cause severe gastroenteritis. After entering the human intestine through contaminated seafood (1.00% NaCl) V. parahaemolyticus will encounter a physiologically related dual pressure environment: low salinity and elevated bile salts (0.03%-0.30%). Although bile salts can affect V. parahaemolyticus under optimal salinity conditions (3.00% NaCl), little is known about their effects on paralysis under low salt conditions (0.90% NaCl) in the intestinal stress environment. This research uniquely simulated this intestinal niche using 0.90% NaCl-0.10% bile salts, revealing its effects on growth kinetics, motility, biofilm formation, and transcriptome responses. The main findings include: significant inhibition of growth (prolonged the lag time (LT)), decreased the maximum specific growth rate (µ

Indexed as

Bile Acids and SaltsTranscriptomeVibrio parahaemolyticusBacterial ProteinsBiofilmsGene Expression ProfilingGene Expression Regulation, BacterialHumansStress, PhysiologicalVibrio InfectionsVirulenceBacterial ProteinsBile Acids and SaltsAdaptation mechanismsLow salt and bile salts environmentTranscriptomeV. parahaemolyticus

Identifiers

PMID41697394

DOI10.1016/j.jbc.2023.104591

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.