ArticleInternational ophthalmology2026
Quantitative analysis of choroidal changes in retinal vein occlusion using ultra-widefield swept-source optical coherence tomography angiography.
Article in International ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
purposeChoroidal alterations are implicated in the pathophysiology of retinal vein occlusion (RVO), yet comprehensive spatial analysis has been limited by conventional imaging. This study aims to leverage ultra-widefield swept-source optical coherence tomography angiography (SS-OCTA) to quantitatively assess spatial changes in the choroidal vascularity index (CVI) and choroidal thickness (CT) in patients with RVO.
methodsThis cross-sectional study included 38 patients with unilateral RVO and 40 healthy controls. Using ultra-widefield SS-OCTA, volumetric CVI and CT were quantified across a 24 × 20 mm area. Data from nine anatomical grids were compared among RVO-affected, contralateral fellow, and healthy control eyes. The correlation between central macular thickness (CMT) and choroidal parameters in RVO eyes was also analyzed.
resultsCompared to controls, RVO-affected eyes showed significantly decreased CVI in the nasal-superior and optic disc grids, and reduced CT in the nasal-superior, optic disc, and nasal-inferior grids. No significant differences in CVI or CT were found between RVO-affected and fellow eyes. In RVO eyes, CMT was negatively correlated with CVI in the nasal-superior and macular grids, but showed no significant correlation with CT.
conclusionUltra-widefield SS-OCTA reveals specific spatial patterns of reduced CVI and CT in RVO, predominantly in the nasal and peripapillary regions. These findings suggest choroidal involvement in RVO includes both vascular and stromal components, and that CVI may serve as a sensitive biomarker for monitoring disease-related choroidal alterations.
Indexed as
Identifiers
41697387What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.