Evidence map›Paper›PMID 41697099›Full record

ArticleActa ophthalmologica2026

Axial length as a risk factor for pseudophakic rhegmatogenous retinal detachment: A Danish registry study.

Ditte-Marie Leegaard Holm, Birgitte Romme Nielsen, Mark Bech Knudsen, Torben Martinussen, Jakob Grauslund, Morten la Cour, Mark Alberti, Therese Grønhøj Krarup

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta ophthalmologica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ditte-Marie Leegaard HolmDepartment of Ophthalmology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.ORCID https://orcid.org/0009-0007-7514-2141
Birgitte Romme NielsenDepartment of Ophthalmology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.ORCID https://orcid.org/0000-0001-9840-8036
Mark Bech KnudsenSection of Biostatistics, University of Copenhagen, Copenhagen, Denmark.
Torben MartinussenSection of Biostatistics, University of Copenhagen, Copenhagen, Denmark.
Jakob GrauslundDepartment of Ophthalmology, Odense University Hospital, Odense, Denmark.
Morten la CourDepartment of Ophthalmology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Mark AlbertiDepartment of Ophthalmology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Therese Grønhøj KrarupDepartment of Ophthalmology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.

Funding

1-årigt Introduktionsstipendium fra Rigshospitalets forskningspuljeCandys Foundation ref. no. 2023-433Den lægevidenskabelige del af Det Sundhedsvidenskabelige Fakultets fond for videnskabeligt ansatte kandidater og studerende ved Københavns Universitet 2023-0021Fight for Sight, DenmarkMauritzen la Fontaine FondenSynoptik-FondenUlla og Bernt Hjejles Mindefond
6 · The paper itself

Abstract

purposeTo examine axial length as a risk factor for pseudophakic rhegmatogenous retinal detachment (pRRD).

methodsWe identified eyes that underwent phacoemulsification between 2 May 2002 and 10 November 2023 and had an axial length registered at the Departments of Ophthalmology in the Capital Region of Denmark or the private clinic Scandinavian Eye Center. The exposure was axial length, and the outcome was time from phacoemulsification to the occurrence of pRRD. The cumulative incidence of pRRD was estimated with the Aalen-Johansen estimator.

resultsWe included 129 362 eyes from 75 316 individuals; 601 eyes developed a pRRD. The eyes were distributed in groups based on axial length: <24 mm: 84 226, 24-25 mm: 38 331 and ≥26 mm: 6805. The hazard of pRRD increased with axial length, and this association was most pronounced in males. Compared to female eyes with an axial length of <24 mm (reference), male eyes of ≥26 mm had a higher hazard of pRRD (hazard ratio (HR) 16.3; 11.8-22.5), and likewise for female eyes of ≥26 (HR: 5.2; 3.3-8.1) after adjustment for age and including an interaction between axial length and sex. The 5-year cumulative incidence of pRRD among male eyes of ≥26 mm undergoing phacoemulsification between the ages 40 and 59 was 9.40% (95%CI: 7.10-12.50), and among male eyes aged ≥60 and of ≥26 mm it was 2.00% (95%CI: 1.50-2.70).

conclusionsThe risk of pRRD increased with axial length, and this association was most pronounced in male eyes. The risk of pRRD was high among male eyes that underwent phacoemulsification between ages 40 and 59.

Indexed as

Axial Length, EyePhacoemulsificationPseudophakiaRegistriesRetinal DetachmentVisual AcuityAgedAged, 80 and overDenmarkFemaleFollow-Up StudiesHumansIncidenceMaleMiddle AgedRetrospective Studiesaxial lengthphacoemulsificationregister‐based studyRhegmatogenous retinal detachment

Identifiers

PMID41697099
PMCPMC13353704

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.