SynthesisMolecular nutrition & food research2026
Human Milk Bioactive Compounds and Allergic- and Infectious-Related Infant Outcomes: A Systematic Review.
Synthesis in Molecular nutrition & food research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Human Milk Bioactive Compounds and Allergic- and Infectious-Related Infant Outcomes: A Systematic Review.Molecular nutrition & food research · 2026Pooled it
- 2'-FL's Depiction of the Human Physiological Function Landscape.Food science & nutrition · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
The impact of Human Milk (HM) bioactive compounds on infant health is crucial yet complex. Current research highlights their role in immune system development and disease prevention. This review aims to synthesize existing literature on the role of HM's bioactive compounds in the onset of diagnosed allergies, immunological diseases, and responses to infectious diseases by infants and children up to 18 years. The systematic review adhered to Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA). A comprehensive search strategy was employed across PubMed, Web of Science, SCOPUS, Scientific Electronic Library Online (SciELO), Cochrane Library, Latin American and Caribbean Health Sciences Literature (LILACS), and LIVIVO. Quality assessment utilized Joanna Briggs Institute checklists for various study designs. Protocol: CRD42023432030. The systematic review encompassed 34 studies, published from 1983 to 2024, representing a total of 9,298 mother-infant dyads. Included studies reported that allergic-related conditions, particularly food allergy, sensitization, and atopic dermatitis, were inversely associated with HM linolenic and linoleic acid. In a meta-analysis of three studies, infants with atopic dermatitis showed lower total omega-3 levels (SMD = -0.46, 95% CI: -1.82 to -0.90, I
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.