Evidence map›Paper›PMID 41696792›Full record

ArticleJournal of the science of food and agriculture2026

Evaluation of antifungal and antimycotoxigenic activity of selected natural antioxidants against Fusarium culmorum: in vitro and in planta assays.

Safa Oufensou, Davide Fabbri, Maria Antonietta Dettori, Paola Carta, Emanuela Azara, Valeria Ugone, Virgilio Balmas, Ismael Malbrán, Quirico Migheli

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Article in Journal of the science of food and agriculture, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

9 authors.

Safa OufensouDipartimento di Agraria, Università degli Studi di Sassari, Sassari, Italy.ORCID https://orcid.org/0000-0003-4766-7251
Davide FabbriIstituto di Chimica Biomolecolare, Consiglio Nazionale delle Ricerche, Sassari, Italy.
Maria Antonietta DettoriIstituto di Chimica Biomolecolare, Consiglio Nazionale delle Ricerche, Sassari, Italy.ORCID https://orcid.org/0000-0002-8776-9271
Paola CartaIstituto di Chimica Biomolecolare, Consiglio Nazionale delle Ricerche, Sassari, Italy.
Emanuela AzaraIstituto di Chimica Biomolecolare, Consiglio Nazionale delle Ricerche, Sassari, Italy.
Valeria UgoneIstituto di Chimica Biomolecolare, Consiglio Nazionale delle Ricerche, Sassari, Italy.
Virgilio BalmasDipartimento di Agraria, Università degli Studi di Sassari, Sassari, Italy.
Ismael MalbránCentro de Investigaciones de Fitopatología (CIDEFI-UNLP-CIC), Facultad de Ciencias Agrarias y Forestales, Universidad Nacional de La Plata, Buenos Aires, Argentina.
Quirico MigheliDipartimento di Agraria, Università degli Studi di Sassari, Sassari, Italy.

Funding

Ministero dell'Università e della Ricerca
6 · The paper itself

Abstract

backgroundFusarium culmorum causes Fusarium head blight (FHB) in cereals, leading to significant yield losses and contamination with type B trichothecene mycotoxins such as deoxynivalenol (DON) and its acetylated derivatives 3-ADON and 15-ADON. Due to the limitations of chemical fungicides, there is increasing interest in sustainable alternatives. Naturally occurring antioxidants have shown potential in modulating fungal growth and mycotoxin production.

resultsThis study evaluated the effects of 11 natural antioxidant compounds on Fusarium culmorum growth and trichothecene production, both in vitro and in planta. In vitro: octyl gallate (7), honokiol (9), and magnolol (10) completely inhibited fungal growth and trichothecene production at 0.5 mmol L

conclusionsNatural antioxidants, particularly octyl gallate and honokiol, represent promising candidates for controlling F. culmorum and reducing trichothecene contamination in cereals. Their application could contribute to safer food by reducing trichothecene levels through environmentally friendly strategies. Further research is needed to optimize formulations and assess field-level efficacy. © 2026 The Author(s). Journal of the Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

Indexed as

AntioxidantsFungicides, IndustrialFusariumMycotoxinsBiphenyl CompoundsPlant DiseasesTrichothecenesAntioxidantsBiphenyl CompoundsdeoxynivalenolFungicides, IndustrialMycotoxinsTrichothecenesantioxidantsfood preservativesFusarium culmorummycotoxinsnatural compounds

Identifiers

PMID41696792
PMCPMC13067071

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.