Evidence map›Paper›PMID 41696771›Full record

ReviewComprehensive reviews in food science and food safety2026

Pulsed Electric Fields for Emerging Single-Cell Bioprocessing in Food Applications: Electropermeabilization Mechanisms and Design Principles.

Byron Perez, Julia Baumgartner, Daniel Macken, Iris Haberkorn, Alexander Mathys

Abstract readReview
In one paragraph

Review in Comprehensive reviews in food science and food safety, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Byron PerezSustainable Food Processing Laboratory, Institute of Food Nutrition and Health, ETH Zurich, Zurich, Switzerland.
Julia BaumgartnerSustainable Food Processing Laboratory, Institute of Food Nutrition and Health, ETH Zurich, Zurich, Switzerland.
Daniel MackenSustainable Food Processing Laboratory, Institute of Food Nutrition and Health, ETH Zurich, Zurich, Switzerland.
Iris HaberkornSingapore-ETH Centre, Singapore, Singapore.
Alexander MathysSustainable Food Processing Laboratory, Institute of Food Nutrition and Health, ETH Zurich, Zurich, Switzerland.ORCID 0000-0003-1633-848X

Funding

Bezos Earth FundCampus for Research Excellence and Technological Enterprise (CREATE) (Award No. NRF2020-THE003-0004 2020)ETH Zurich Foundation 2023-HS-430National Research Foundation SingaporeSwiss National Science Foundation 198750
6 · The paper itself

Abstract

This review evaluates pulsed electric fields (PEF) as an emerging platform for single-cell bioprocessing in food applications. Connections are drawn between key mechanisms in electropermeabilization and applications, and a practical PEF process design framework is provided. Electropermeabilization is governed by electrical parameters, physicochemical conditions, cellular traits, and system-level variables such as chamber geometry and residence time. Furthermore, cell densities and organism choice critically influence processing outcomes. Linking mechanistic understanding and practical applications, this holistic approach aims to increase reproducibility and scalability in PEF-based single-cell bioprocessing in the food sector.

Indexed as

ElectricityElectroporationFood HandlingSingle-Cell Analysis

Identifiers

PMID41696771
PMCPMC12908215

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.