ArticleFrontiers in neurology2025
Prognostic influences and prediction model construction for traumatic cervical spinal cord injury.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Targeting the Gut-Brain-Ferroptosis Axis: Molecular Mechanisms and Therapeutic Potential in Alzheimer's Disease and Epilepsy.Journal of molecular neuroscience : MN · 2026Review
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6 authors.
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Abstract
Study design: Retrospective analysis of prognostic factors in traumatic cervical spinal cord injury (TCSCI) patients. Objective: Explore a novel approach for the prognosis assessment of TCSCI. Methods: A retrospective analysis of clinical data was conducted on patients who underwent operation at Xi'an Honghui Hospital between March 2016 and May 2023. The study included sex, age, hypertension, diabetes mellitus (DM), damage range, ossification of the posterior longitudinal ligament (OPLL), cervical spinal canal stenosis grading (CSCS), surgical timing, and postoperative complications (deep vein thrombosis, pulmonary complications, pressure ulcers, and urinary tract infections). A prognostic model was established by these differential factors and evaluating the sensitivity and specificity for predicting paralysis occurrence. Results: Paralysis was found to be 4.009 times more likely in patients with DM compared to those without (95% CI: 1.250-12.863, Conclusion: The prognosis of TCSCI is influenced by factors including DM, damage range, CSCS, surgical timing, and the number of postoperative complications. A clinical prognostic model was developed based on these prognostic factors, demonstrating a strong predictive capability for paralysis.
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