ArticleJournal of traditional and complementary medicine2026
Herbal dietary supplements for erectile dysfunction: A systematic review and meta-analysis of randomized-controlled trials.
Article in Journal of traditional and complementary medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Flavonoid Composition and Molecular Basis of the Potential Sexual-Enhancing Properties of aPharmaceuticals (Basel, Switzerland) · 2026Article
- Plant-derived bioactives in depression-related and antidepressant-associated sexual dysfunction: a narrative review.Frontiers in nutrition · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and aim: Interest of herbal supplements as alternatives to conventional treatments for erectile dysfunction (ED) has increased markedly. This systematic review and meta-analysis aimed to evaluate the effectiveness of herbal supplements in treating ED. Experimental procedure: Pubmed, Embase, and Cochrane CENTRAL databases were searched for relevant studies published until June 1, 2023. Randomized controlled trials (RCTs) evaluating herbal supplements for ED compared to a placebo or no intervention were eligible for inclusion. The outcomes of interest included erectile function, orgasmic function, sexual desire, subjective satisfaction, and serum testosterone levels. Results and conclusion: Fourteen RCTs with a total of 1227 males with ED were included. Mean age of study participants ranged from 35 to 65 years; and follow-up ranged from 1 month to 6 months. Herbal dietary supplements had a significant, positive effect on erectile function (standard mean difference (SMD) = 1.20, 95 % confidence interval (CI): 0.64-1.76), orgasmic function (SMD = 1.09, 95 % CI: 0.34-1.83), sexual desire (SMD = 1.02, 95 % CI: 0.45-1.60), intercourse satisfaction (SMD = 1.48, 95 % CI: 0.83-2.13), overall satisfaction (SMD = 0.93, 95 % CI: 0.45-1.40), and serum testosterone level (SMD = 0.54, 95 % CI: 0.04-1.05) compared to effects in the control groups. Saffron was effective in improving erectile function, orgasmic function, and intercourse satisfaction, while ginseng benefited erectile function, orgasmic function, sexual desire, overall satisfaction, and serum testosterone levels. In contrast, evidence for other agents such as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.