ArticleJPRAS open2026
Evaluating the potential of quantitative assessment of intraoperative fasciocutaneous flap perfusion using microscope-integrated indocyanine green fluorescence angiography.
Article in JPRAS open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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9 authors.
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Abstract
Background: Perfusion-related complications are a leading cause of morbidity and flap loss in reconstructive surgery. While indocyanine green fluorescence angiography (ICG-FA) is commonly used, its subjective interpretation may miss early signs of perfusion disturbances. Quantitative ICG-FA (Q-ICG-FA) offers a more objective method, but its potential in fasciocutaneous flaps remains insufficiently studied. Methods: This retrospective study analyzed intraoperative ICG-FA data from patients undergoing fasciocutaneous flap reconstruction. Fluorescence-time curves (FTCs) were generated from three regions of interest (ROIs): reference tissue (ROI1), proximal flap (ROI2), and distal flap (ROI3). FTCs and derived quantitative parameters, including time-to-peak (Ttp) and normalized inflow/outflow slopes, were compared between patients with (PRC) and without (No PRC) perfusion-related complications. Results: Twenty patients were included. Seven patients experienced a perfusion-related complication, most commonly venous congestion ( Conclusion: Q-ICG-FA objectively distinguished flaps with and without perfusion-related complications. Dynamic parameters, particularly Ttp and inflow/outflow slopes, were most associated with perfusion compromise. Larger studies are needed to validate these findings.
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