Evidence map›Paper›PMID 41696550›Full record

ArticleAnnals of internal medicine. Clinical cases2026

Report of Concomitant Intracranial Cysts in Unrelated Patients With Heterozygous Germline

Ehab Y Harahsheh, Erin Merritt, Judy B Tejon, Bukola A Olarewaju, Misha B Asif, Dusica Babovic-Vuksanovic, Mayowa A Osundiji

Abstract read
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In one paragraph

Article in Annals of internal medicine. Clinical cases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ehab Y HarahshehDepartment of Neurology, Mayo Clinic, Phoenix, Arizona.
Erin MerrittDepartment of Biological Sciences, Arizona State University, Phoenix, Arizona.
Judy B TejonDepartment of Clinical Genomics, Mayo Clinic, Scottsdale, Arizona.
Bukola A OlarewajuSchool of Science and Engineering, University of Dundee, Nethergate, Dundee, United Kingdom.
Misha B AsifDepartment of Clinical Genomics, Mayo Clinic, Scottsdale, Arizona.
Dusica Babovic-VuksanovicDepartment of Clinical Genomics, Mayo Clinic, Rochester, Minnesota.
Mayowa A OsundijiDepartment of Clinical Genomics, Mayo Clinic, Scottsdale, Arizona.

Funding

Expert curation of sequence variants in the proximal urea cycle genesU24HD108087 · NICHD · CHILDREN'S RESEARCH INSTITUTE · PI AH MEW, NICHOLAS, CALDOVIC, LJUBICA MORIZONO · 2023 to 2025
$1.2M
NICHD NIH HHS U24 HD108087
6 · The paper itself

Abstract

Neurofibromatosis 1 (NF1) is one of the most common genetic diseases of the central nervous system. The nature of intracranial lesions that are associated with NF1 are yet to be fully defined. Arachnoid, velum interpositum, and odontogenic cysts are among the more common intracranial cystic lesions that can be congenital. Although odontogenic cysts are well known to be associated with Gorlin-Goltz syndrome, the possibilities of other genetic disorders in patients with odontogenic and other intracranial cystic lesions have continued to stir research interests. Here, we report 2 cases of unrelated patients, each patient having concurrent intracranial cystic lesions in the setting of a diagnosis of NF1. Individual I had concomitant arachnoid and odontogenic cysts in parallel with a novel heterozygous germline

Indexed as

ADHDArachnoidCystCystsDiagnostic medicineDifferential diagnosisGenetic diseasesGeneticsGenetic testingGenomicsIntracranialLesionsNF1OdontogenicPathogenesis

Identifiers

PMID41696550
PMCPMC12904477

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.