Evidence map›Paper›PMID 41696528›Full record

ArticleResuscitation plus2026

Wolf Creek XVIII Part 7: strategies to optimize international collaborations in cardiac arrest research.

Yohei Okada, Janet E Bray, Robert W Neumar, Bryan F McNally, Markus B Skrifvars, Laurie J Morrison, Niklas Nielsen, Theresa Olasveengen, Marcus E H Ong

Abstract read
In one paragraph

Article in Resuscitation plus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yohei OkadaPre-hospital and Emergency Research Centre, Health Services Research and Population Health, Duke-NUS Medical School, Singapore, Singapore.
Janet E BraySchool of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
Robert W NeumarDepartment of Emergency Medicine and Department of Molecular & Integrative Physiology, University of Michigan Medical School, Ann Arbor, MI, USA.
Bryan F McNallyDepartment of Emergency Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Markus B SkrifvarsDepartment of Anaesthesiology and Intensive Care Medicine, Helsinki University Hospital and University of Helsinki, Finland.
Laurie J MorrisonDivision of Emergency Medicine, Department of Medicine, University of Toronto, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
Niklas NielsenDepartment of Clinical Sciences Lund, Anesthesiology and Intensive Care, Lund University, Lund and Department of Anesthesiology and Intensive Care, Helsingborg Hospital, Helsingborg, Sweden.
Theresa OlasveengenInstitute for Clinical Medicine, University of Oslo and Department of Anesthesia and Intensive Care Medicine, Oslo University Hospital, Oslo, Norway.
Marcus E H OngPre-hospital and Emergency Research Centre, Health Services Research and Population Health, Duke-NUS Medical School, Singapore, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: International collaborations in research for cardiac arrest are much needed to advance the science, translate this into practice and implement for impact. However, barriers and challenges remain for international collaboration. This paper aims to summarize the key discussions and consensus recommendations from the Wolf Creek XVIII Conference, focusing on strategies to optimize international collaborations in cardiac arrest research. Methods: The 50th Anniversary Wolf Creek XVIII Conference was hosted by the Max Harry Weil Institute for Critical Care Research and Innovation in Ann Arbor, Michigan, USA on June 19-21, 2025. Strategies to Optimize International Collaborations in Cardiac Arrest Research was a topic of focused presentations and discussions by invited panelists and conference participants, made up of international academic and industry scientists, as well as thought leaders in the field of cardiac arrest resuscitation. An expert panel gave perspectives and insights that were debated and feedback was given by participants. Results: Discussions were organized into three domains: registry research, basic science and translational research, and clinical trials. Several large-scale registries have collectively advanced data-driven resuscitation science through collaboration and mutual learning, while continuing to face challenges related to heterogeneity, privacy regulation, and data lag. Successful models like the Global Out-of-Hospital Cardiac Arrest Registries (GOHCAR) consortium highlight the importance of trust and sustained engagement. In preclinical research, the Transcontinental Cardiac Arrest Experimental Network for Discovery (TRANSCEND) aims to harmonize international laboratory studies. Clinical collaboration is progressing through multicenter randomized controlled trials such as the Sedation, temperature and pressure after cardiac arrest and resuscitation (STEPCARE), promoting inclusive, adaptive global research. Conclusion: Sustained international collaboration across registries, laboratory studies, and clinical trials is key for advancing resuscitation science. By fostering trust, harmonization, and capacity building, these global networks can accelerate discovery and improve outcomes across cardiac arrest and other time-critical conditions.

Indexed as

Clinical trialGlobal collaborationPreclinical researchRegistry

Identifiers

PMID41696528
PMCPMC12906194

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.