Evidence map›Paper›PMID 41696321›Full record

ArticleACS omega2026

Nobiletin Ameliorates Doxorubicin-Induced Nephrotoxicity by Targeting Oxidative Stress, Inflammatory, and Apoptotic Pathways: Combined

Sümeyra Çetinkaya, İpek Süntar, Mürşide Ayşe Demirel, İlknur Çınar Ayan, Özen Akarca Dizakar

Abstract read
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sümeyra ÇetinkayaBiotechnology Research Center, Field Crops Central Research Institute, Ankara 06170, Türkiye.
İpek SüntarDepartment of Pharmacognosy, Faculty of Pharmacy, Gazi University, Ankara 06630, Türkiye.ORCID https://orcid.org/0000-0003-4201-1325
Mürşide Ayşe DemirelDepartment of Basic Pharmaceutical Sciences, Faculty of Pharmacy, Gazi University, Ankara 06630, Türkiye.
İlknur Çınar AyanDepartment of Medical Biology, Faculty of Medicine, Necmettin Erbakan University, Konya 42090, Türkiye.
Özen Akarca DizakarDepartment of Histology and Embryology, Faculty of Medicine, Bakırçay University, İzmir 35665, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Doxorubicin (DOX), although effective as a chemotherapeutic agent, induces significant nephrotoxicity, limiting its clinical application. This study investigated the nephroprotective potential of nobiletin and tangeretin, in comparison with the reference compound silymarin, against DOX-induced acute kidney injury (AKI) in rats. DOX administration significantly increased the kidney-to-body weight ratio (

Identifiers

PMID41696321
PMCPMC12902976

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.