Evidence map›Paper›PMID 41696199›Full record

ArticleACS omega2026

Immunohistochemical Evaluation of Spinal Cord Injuries Treated with Amniotic Membrane.

Leonardo B de Lima, Débora C C Correia, Luciana B Sant'anna, Emilia A L S Arisawa

Abstract read
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Leonardo B de LimaBiostimulation and Tissue Repair Laboratory, Development and Research Institute (IP&D), Universidade Do Vale Do Paraíba- UNIVAP, Av. Shishima Hifumi, 2911, Urbanova, São José dos Campos, São Paulo 12244-000, Brazil.ORCID https://orcid.org/0009-0007-8582-8489
Débora C C CorreiaBiostimulation and Tissue Repair Laboratory, Development and Research Institute (IP&D), Universidade Do Vale Do Paraíba- UNIVAP, Av. Shishima Hifumi, 2911, Urbanova, São José dos Campos, São Paulo 12244-000, Brazil.ORCID https://orcid.org/0000-0001-5959-7428
Luciana B Sant'annaBiostimulation and Tissue Repair Laboratory, Development and Research Institute (IP&D), Universidade Do Vale Do Paraíba- UNIVAP, Av. Shishima Hifumi, 2911, Urbanova, São José dos Campos, São Paulo 12244-000, Brazil.ORCID https://orcid.org/0000-0002-5128-7414
Emilia A L S ArisawaBiostimulation and Tissue Repair Laboratory, Development and Research Institute (IP&D), Universidade Do Vale Do Paraíba- UNIVAP, Av. Shishima Hifumi, 2911, Urbanova, São José dos Campos, São Paulo 12244-000, Brazil.ORCID https://orcid.org/0000-0003-3526-3890

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spinal cord injury (SCI) severely disrupts central nervous system (CNS) function by interrupting sensory and motor signal transmission, often resulting in permanent deficits due to the formation of a glial scar. Although the amniotic membrane (AM) is derived from the human placenta and is a promising biomaterial, its efficacy in treating SCI remains unexplored. This study investigates the therapeutic potential of AM fragments in a surgically induced acute SCI model in rats, focusing on preserving tissue integrity and modulating astrocyte distribution and reactivity. SCI was experimentally induced by a drop-weight mini-guillotine model in rats, which were subsequently allocated into three groups: Control (C), Injury (I), and Amniotic Membrane (AM), where a 4 cm

Identifiers

PMID41696199
PMCPMC12902973

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.