ArticleACS omega2026
Gold Nanorods Enable Rapid and Label-Free SARS-CoV‑2 Detection through LAMP Assay.
Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
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Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nanoscale noble metals exhibit unique optical properties due to localized surface plasmon resonance (LSPR), which occurs within the visible range of the electromagnetic spectrum. This property has facilitated their extensive use as transducers in biosensor platforms. Among these, gold nanoparticlesparticularly gold nanorods (AuNRs)have gained significant attention owing to their superior plasmonic characteristics. Their anisotropic shape generates two distinct plasmonic bands, enhancing light absorption, scattering, and sensitivity to environmental changes. Here, we present a biosensing approach for detecting the SARS-CoV-2 genetic material amplified via loop-mediated isothermal amplification (LAMP), using AuNRs as transducers to generate dynamic light scattering signals captured by a custom-built depolarized dynamic light scattering (DDLS) apparatus. This strategy reduces the conventional LAMP reaction time to 20 min and allows direct detection of target amplicons, representing a substantial improvement over traditional indirect detection methods that are often prone to false results. Clear discrimination between negative and positive samples was achieved using both control reactions and clinical specimens, demonstrating the potential of integrating AuNR-based transducers with LAMP and DDLS into an efficient, rapid, and highly sensitive diagnostic platform.
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Registered trials
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