Evidence map›Paper›PMID 41696011›Full record

ArticleFrontiers in veterinary science2026

Case Report: Anaesthetic management in a canine patient with severe atrioventricular septal defect and pulmonary hypertension undergoing non-cardiac surgery.

Claire Nicol, Karin Kriström, Vanessa Bettembourg

Abstract readCase Reports
In one paragraph

Article in Frontiers in veterinary science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Claire NicolEvidensia Södra Animal Hospital Kungens Kurva, Stockholm, Sweden.
Karin KriströmEvidensia Södra Animal Hospital Kungens Kurva, Stockholm, Sweden.
Vanessa BettembourgEvidensia Södra Animal Hospital Kungens Kurva, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: A 9-year-old, 6.8-kg intact male Petit Brabançon with a congenital partial atrioventricular septal defect (AVSD) presented for dental extractions. Pre-anaesthetic echocardiographic assessment revealed a large ostium primum atrial septal defect with bidirectional interatrial shunting, severe right atrial and ventricular enlargement, abnormal atrioventricular valves with severe tricuspid regurgitation, mild relative pulmonic stenosis, and moderate pulmonary hypertension (PH). Anaesthetic goals were to minimize increases in pulmonary vascular resistance (PVR), preserve right ventricular perfusion and cardiac output (CO), and avoid alterations in intracardiac shunt dynamics that could promote right-to-left shunting. Premedication consisted of methadone [0.2 mg/kg intramuscularly (IM)], lidocaine (1 mg/kg intravenously (IV)) and midazolam (0.3 mg/kg IV). Continuous infusions of lidocaine (30-50 μg/kg/min) and remifentanil (10-30 μg/kg/h) were used as inhalant minimum alveolar concentration (MAC)-sparing analgesic adjuncts. Anaesthesia was induced with ketamine (1 mg/kg IV) and propofol (2 mg/kg IV) and maintained with sevoflurane in oxygen and air. Controlled ventilation targeted normocapnia and the fraction of inspired oxygen (FiO₂) was titrated to maintain pulse oximeter (SpO₂) values above 95%, while avoiding unnecessary hyperoxia. A norepinephrine infusion (0.2-0.4 μg/kg/min) supported mean arterial pressure (MAP) > 65 mmHg. Regional dental nerve blocks supplemented analgesia. Fourteen teeth were extracted during a 64-min anaesthetic. Recovery was complicated by transient hypoxemia attributed to upper airway obstruction, resolving with oxygen supplementation and nebulized adrenaline. Outcome: No arrhythmias or sustained right-to-left shunting occurred. The dog was discharged the same day and returned to normal activity. Survival after the procedure was 14 months before euthanasia for acute respiratory decompensation. Clinical relevance: This report highlights practical, physiology-guided strategies to conduct anaesthesia in non-cardiac procedures in dogs with severe AVSD and PH, in hospital settings without advanced equipment such as intra-operative transesophageal echocardiography or direct CO measurements. It also serves as a reminder not to let the anaesthetic risk in patients with severe cardiac disease be the reason for refraining from quality of life improving dental procedures.

Indexed as

cardiac anaesthesiacase reportcongenital defectdental proceduredog

Identifiers

PMID41696011
PMCPMC12893945

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.