Evidence map›Paper›PMID 41695970›Full record

ArticleGastro hep advances2026

Lower Health Literacy Is Associated With Greater Severity of Metabolic Dysfunction and Steatotic Liver Disease.

Alana Saddic, Jessica N Mittler, Ekaterina Smirnova, Deborah DiazGranados, Arun J Sanyal

Abstract read
In one paragraph

Article in Gastro hep advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alana SaddicStravitz-Sanyal Institute for Liver Disease and Metabolic Health, VCU School of Medicine, Richmond, Virginia.
Jessica N MittlerDepartment of Health Administration, College of Health Professions, Virginia Commonwealth University, Richmond, Virginia.
Ekaterina SmirnovaDepartment of Biostatistics, Virginia Commonwealth University, Richmond, Virginia.
Deborah DiazGranadosPsychiatry Department, School of Medicine, Virginia Commonwealth University, Richmond, Virginia.
Arun J SanyalStravitz-Sanyal Institute for Liver Disease and Metabolic Health, VCU School of Medicine, Richmond, Virginia.

Funding

Wright Regional Center for Clinical and Translational ScienceUM1TR004360 · NCATS · VIRGINIA COMMONWEALTH UNIVERSITY · PI FREDERICK Gerard MOELLER · 2023 to 2026
$16.3M
Predicting outcomes in nonalcoholic steatohepatitis with advanced fibrosisR01DK129564 · NIDDK · VIRGINIA COMMONWEALTH UNIVERSITY · PI ARUN J SANYAL, Mohammad Shadab Siddiqui · 2022 to 2026
$2.8M
NCATS NIH HHS UM1 TR004360NIDDK NIH HHS R01 DK129564
6 · The paper itself

Abstract

Background and Aims: The spectrum of health literacy in metabolic dysfunction-associated steatotic liver disease (MASLD) patients and its relationship to disease severity are largely unknown. We performed an exploratory cross-sectional study regarding health literacy in this population. Methods: The Health Literacy Questionnaire (HLQ) was administered to 101 individuals with MASLD attending an ambulatory hepatology clinic; data were obtained from medical records. Scores per HLQ scale were related to disease severity by Spearman coefficient, Results: In HLQ part 1 (scored 1-4), the highest scoring scale was feeling understood and supported by health-care providers (mean ± standard deviation) (3.43 ± 0.6). In HLQ part 2 (scored 1-5), the highest scoring scale was understanding health information well enough to know what to do (4.12 ± 0.57). In HLQ part 1, the lowest scoring scale was actively managing health (2.98 ± 0.6). In HLQ part 2, the lowest scoring scale was navigating the health system (3.83 ± 0.71). A decreased ability to actively manage health was associated with higher liver steatosis (r = -0.29, Conclusion: Lower education and health literacy are associated with more advanced MASLD and metabolic dysfunction.

Indexed as

DisparitiesHealth LiteracyHLQMetabolic Dysfunction–Associated Steatotic Liver Disease (MASLD)Social Determinants of Health

Identifiers

PMID41695970
PMCPMC12906003

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.