Evidence map›Paper›PMID 41695933›Full record

ArticleWorld journal of gastrointestinal oncology2026

Total neoadjuvant therapy in rectal cancer: Challenging traditions without compromising surgical safety.

Riya Karmakar, Aditya Kandalkar, Arvind Mukundan

Abstract readEditorial
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of gastrointestinal oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Riya KarmakarSchool of Engineering and Technology, Sanjivani University, Kopargaon 423603, Maharashtra, India.
Aditya KandalkarDepartment of Information Technology, Sanjivani College of Engineering, Kopargaon 423603, Maharashtra, India.
Arvind MukundanSchool of Engineering and Technology, Sanjivani University, Kopargaon 423603, Maharashtra, India. arvindmukund96@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Total neoadjuvant therapy (TNT) is swiftly transforming the therapeutic approach for locally advanced rectal cancer; yet, its integration as a standard practice necessitates meticulous evaluation of surgical safety, long-term outcomes, and patient-centered considerations. The research conducted by Jabbar

Indexed as

ChemoradiotherapyFOLFIRINOXMultimodal therapyOncologyOrgan preservationRectal cancerRectal Cancer and Preoperative Induction therapy followed by Dedicated Operation trialSurgical safetyTotal mesorectal excisionTotal neoadjuvant therapy

Identifiers

PMID41695933
PMCPMC12898685

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.