ArticleWorld journal of gastrointestinal surgery2026
Neutrophil-lymphocyte ratio, albumin-alkaline phosphatase ratio, and bilirubin predict outcomes in hepatectomy hepatolithiasis patients.
Article in World journal of gastrointestinal surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundHepatolithiasis is a common disease whose key treatment modality is hepatectomy. However, postoperative complications are common and can adversely affect the therapeutic outcomes. The analysis of clinical data is essential to prevent a poor prognosis following hepatectomy.
aimTo determine the prognostic value of the neutrophil-to-lymphocyte ratio (NLR), albumin/alkaline phosphatase ratio (ALB/ALP), and total bilirubin (TBIL) levels in hepatolithiasis hepatectomy.
methodsWe retrospectively studied 135 patients with hepatolithiasis who underwent hepatectomy between March 2021 and August 2023. The patients were stratified into good and poor prognosis groups. We compared the general data and peripheral blood levels of NLR, ALB/ALP, and TBIL. Multivariate logistic regression was used to identify factors influencing poor prognosis, and the predictive value of these biomarkers was assessed using receiver operating characteristic (ROC) curve analysis.
resultsOf 135 patients, 41 had poor prognosis. Comparative analysis revealed this group had significantly higher proportions of patients with an American Society of Anesthesiologists (ASA) score ≥ grade II, intraoperative blood transfusion, and a history of hepatobiliary surgery. These patients also had a lower anatomical hepatectomy rate and significantly greater intraoperative blood loss (
conclusionThe independent risk factors for poor post-hepatectomy prognosis were identified as ASA ≥ II, non-anatomical resection, high blood loss, transfusion, and prior surgery; NLR, ALB/ALP, and TBIL also held predictive value.
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